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采用外侧胸区的微血管组织转移进行糖尿病足表面重建。

Diabetic foot resurfacing using microvascular tissue transfer from lateral thoracic region.

机构信息

Department of Plastic and Reconstructive Surgery, College of Medicine, Hanyang University, Seoul, Korea.

Shanghai MK Medical Cosmetic Surgery Clinic, Shanghai, China.

出版信息

Diabetes Metab Res Rev. 2023 Feb;39(2):e3593. doi: 10.1002/dmrr.3593. Epub 2022 Nov 28.

Abstract

AIMS

Diabetic foot ulcer is a major complication of diabetes mellitus and amputation is often needed. Since mortality rate after amputation is comparatively high, saving diabetic foot is required not only for preserving function and life quality, but also for decreasing mortality rate. This study was designed to analyse experience of limb salvage in patients with diabetic foot using free flaps from the lateral thoracic region over a 10-year period.

MATERIALS AND METHODS

Between 2009 and 2018, 297 cases of diabetic foot underwent surgical procedures. We analysed the 83 cases who underwent free flap from lateral thoracic region. Patient data were reviewed retrospectively.

RESULTS

A total of 83 patients, 56 of them males, were included in this study. Age of patients ranged from 27 to 80 years. Twenty patients underwent percutaneous transluminal angioplasty procedures. The latissimus dorsi muscle sparing technique was used in 7 cases. A thoracodorsal artery perforator flap was used in 68 cases. A thoracodorsal artery perforator chimaeric flap was performed in 8 cases. The flap survival rate was 98.8% and the limb salvage rate was 96.4%. The mean follow-up was 6.5 years. During follow-up 14 patients suffered recurrence of foot ulcers.

CONCLUSIONS

Ten-year experience of using flaps from the lateral thoracic region revealed superior outcomes in terms of flap survival and limb saving compared to those in a recent meta-analysis and other reports. Long vascular pedicle technique and the chimaeric technique might be the alternative methods for multiple or vascular insufficient diabetic foot defects.

摘要

目的

糖尿病足溃疡是糖尿病的主要并发症,常需要截肢。由于截肢后的死亡率相对较高,因此不仅需要保存糖尿病足以维持功能和生活质量,还需要降低死亡率。本研究旨在分析 10 年来使用胸外侧游离皮瓣保肢治疗糖尿病足患者的经验。

材料和方法

2009 年至 2018 年间,297 例糖尿病足患者接受了手术治疗。我们分析了 83 例接受胸外侧游离皮瓣的患者。回顾性分析患者资料。

结果

共有 83 例患者(56 例男性)纳入本研究。患者年龄为 27 至 80 岁。20 例患者接受经皮腔内血管成形术治疗。7 例采用保留背阔肌技术。68 例患者采用胸背动脉穿支皮瓣,8 例患者采用胸背动脉穿支复合皮瓣。皮瓣成活率为 98.8%,保肢率为 96.4%。平均随访时间为 6.5 年。随访期间,14 例患者足部溃疡复发。

结论

10 年使用胸外侧皮瓣的经验表明,与近期的荟萃分析和其他报道相比,在皮瓣成活率和保肢方面具有更好的效果。长血管蒂技术和复合技术可能是治疗多发性或血管不足的糖尿病足缺损的替代方法。

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