YaHS：另一个 Hi-C 支架工具。
YaHS: yet another Hi-C scaffolding tool.
机构信息
Department of Genetics, University of Cambridge, Cambridge CB2 3EH, UK.
Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge CB10 1SA, UK.
出版信息
Bioinformatics. 2023 Jan 1;39(1). doi: 10.1093/bioinformatics/btac808.
SUMMARY
We present YaHS, a user-friendly command-line tool for the construction of chromosome-scale scaffolds from Hi-C data. It can be run with a single-line command, requires minimal input from users (an assembly file and an alignment file) which is compatible with similar tools and provides assembly results in multiple formats, thereby enabling rapid, robust and scalable construction of high-quality genome assemblies with high accuracy and contiguity.
AVAILABILITY AND IMPLEMENTATION
YaHS is implemented in C and licensed under the MIT License. The source code, documentation and tutorial are available at https://github.com/sanger-tol/yahs.
SUPPLEMENTARY INFORMATION
Supplementary data are available at Bioinformatics online.
摘要
我们介绍了 YaHS，这是一个用于从 Hi-C 数据构建染色体尺度支架的用户友好型命令行工具。它可以用单行命令运行，只需用户提供最少的输入（一个组装文件和一个比对文件），与类似的工具兼容，并以多种格式提供组装结果，从而能够快速、稳健和可扩展地构建具有高精度和连续性的高质量基因组组装。
可用性和实现
YaHS 是用 C 语言编写的，并根据麻省理工学院的许可证授权。源代码、文档和教程可在 https://github.com/sanger-tol/yahs 上获得。
补充信息
补充数据可在《生物信息学》在线获得。
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