美国成年人长冠状病毒病的流行病学。

The Epidemiology of Long Coronavirus Disease in US Adults.

机构信息

Institute for Implementation Science in Population Health (ISPH), City University of New York (CUNY), New York, New York, USA.

Department of Epidemiology and Biostatistics, Graduate School of Public Health and Health Policy, City University of New York (CUNY), New York, New York, USA.

出版信息

Clin Infect Dis. 2023 May 3;76(9):1636-1645. doi: 10.1093/cid/ciac961.

DOI:10.1093/cid/ciac961

PMID:36542514

Abstract

BACKGROUND

We estimated the prevalence of long COVID and impact on daily living among a representative sample of adults in the United States.

METHODS

We conducted a population-representative survey, 30 June-2 July 2022, of a random sample of 3042 US adults aged 18 years or older and weighted to the 2020 US population. Using questions developed by the UK's Office of National Statistics, we estimated the prevalence of long COVID, by sociodemographics, adjusting for gender and age.

RESULTS

An estimated 7.3% (95% confidence interval: 6.1-8.5%) of all respondents reported long COVID, corresponding to approximately 18 828 696 adults. One-quarter (25.3% [18.2-32.4%]) of respondents with long COVID reported their day-to-day activities were impacted "a lot" and 28.9% had severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection more than 12 months ago. The prevalence of long COVID was higher among respondents who were female (adjusted prevalence ratio [aPR]: 1.84 [1.40-2.42]), had comorbidities (aPR: 1.55 [1.19-2.00]), or were not (vs were) boosted (aPR: 1.67 [1.19-2.34]) or not vaccinated (vs boosted) (aPR: 1.41 [1.05-1.91]).

CONCLUSIONS

We observed a high burden of long COVID, substantial variability in prevalence of SARS-CoV-2, and risk factors unique from SARS-CoV-2 risk, suggesting areas for future research. Population-based surveys are an important surveillance tool and supplement to ongoing efforts to monitor long COVID.

摘要

背景

我们估计了美国代表性成年人样本中长新冠的流行率及其对日常生活的影响。

方法

我们于 2022 年 6 月 30 日至 7 月 2 日进行了一项具有代表性的人口调查，调查对象为年龄在 18 岁及以上的 3042 名美国成年人，并根据 2020 年美国人口进行了加权。我们使用英国国家统计局开发的问题，根据社会人口统计学因素，调整性别和年龄，估计长新冠的流行率。

结果

估计所有受访者中，有 7.3%（95%置信区间：6.1-8.5%）报告患有长新冠，相当于约 18828696 名成年人。有四分之一（25.3%[18.2-32.4%]）患有长新冠的受访者表示，他们的日常活动受到了“很大”影响，28.9%的人在 12 个月前感染了严重急性呼吸综合征冠状病毒 2（SARS-CoV-2）。在女性（调整后患病率比[aPR]：1.84[1.40-2.42]）、患有合并症（aPR：1.55[1.19-2.00]）或未接种疫苗（vs 接种疫苗）（aPR：1.41[1.05-1.91]）的受访者中，长新冠的患病率更高。