Department of Surgery, Vanderbilt University Medical Center, Preston Research Building, 2220 Pierce Avenue, Nashville, Tennessee, 37232-6860, USA.
Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
World J Surg Oncol. 2023 Jan 30;21(1):24. doi: 10.1186/s12957-023-02885-2.
Synovial sarcoma is a rare soft tissue sarcoma which frequently involves the upper or lower extremities. Soft tissue sarcomas including synovial sarcoma have a propensity to metastasize to the lungs, and there are very few reports of metastatic lesions in other locations.Here, we report a case of a 49-year-old patient who underwent neoadjuvant chemoradiation for an upper extremity synovial sarcoma and presented approximately 4 years later with abdominal pain and hemoperitoneum and was ultimately found to have metastatic synovial sarcoma involving the greater curvature of the stomach and surrounding peri-gastric soft tissue. We describe the multidisciplinary management of this complex patient presentation and propose that expanded surveillance imaging beyond that of the local tumor resection bed and the chest may be beneficial especially in tumors with high-risk features.
滑膜肉瘤是一种罕见的软组织肉瘤,常累及上肢或下肢。软组织肉瘤包括滑膜肉瘤,有向肺部转移的倾向,其他部位转移病灶非常少见。在此,我们报告一例 49 岁患者,因上肢滑膜肉瘤接受新辅助放化疗,约 4 年后出现腹痛和血腹,最终发现胃大弯和周围胃周软组织有转移性滑膜肉瘤。我们描述了这例复杂患者的多学科管理,并提出除局部肿瘤切除床和胸部外,扩大监测影像可能有益,尤其是在具有高危特征的肿瘤中。