Department of Public Health, Epidemiology Unit, Provincial Health Authority of Siracusa.
Siracusa Cancer Registry, Provincial Health Authority of Siracusa.
J Prev Med Hyg. 2022 Dec 31;63(4):E513-E519. doi: 10.15167/2421-4248/jpmh2022.63.4.2587. eCollection 2022 Dec.
The COVID-19 pandemic has severely impacted routine immunization activities and a decline in vaccination coverage has been documented around the world. The aim of this study was to assess the impact of the direct and indirect effects of the COVID-19 pandemic on routine childhood vaccination coverage in the Province of Siracusa, Italy.
We compared 2020 and 2019 vaccination coverage by age group and vaccine type. Results were considered statistically significant at a two-tailed p-value ≤ 0.05.
Our findings show that vaccination coverage rates for mandatory and recommended vaccinations decreased in 2020 compared with the previous year (range from -1.4% to -7.8%). Anti-rotavirus vaccination increased (+4.8%, as compared to 2019), while the reductions observed for polio vaccination (hexavalent) and human papillomavirus vaccination in males were not statistically significant. The reduction did not hit the population in the same manner, with the greater decreases observed for children aged > 24 months compared to the younger (-5.7% vs -2.2%) and for booster doses compared to the primary vaccinations (-6.4% vs -2.6%).
This study found that vaccination coverage of routine childhood immunisations was negatively affected during the COVID-19 pandemic in the Province of Siracusa. It is of huge importance to put in place some catch-up programs to ensure vaccinations at the earliest of individuals who missed immunization during the pandemic.
COVID-19 大流行严重影响了常规免疫活动,并且已在全球范围内记录到疫苗接种率下降。本研究旨在评估 COVID-19 大流行对意大利锡拉库萨省常规儿童疫苗接种覆盖率的直接和间接影响。
我们按年龄组和疫苗类型比较了 2020 年和 2019 年的疫苗接种覆盖率。当双侧 p 值≤0.05 时,结果被认为具有统计学意义。
我们的研究结果表明,与前一年相比,2020 年强制性和推荐性疫苗接种率下降(范围为-1.4%至-7.8%)。抗轮状病毒疫苗接种有所增加(比 2019 年增加了 4.8%),而观察到的脊髓灰质炎(六价)疫苗和男性 HPV 疫苗接种减少则无统计学意义。这种减少并没有以相同的方式影响人群,对于 24 个月以上的儿童,其减少幅度大于 24 个月以下的儿童(-5.7%比-2.2%),对于加强剂次,其减少幅度大于基础免疫(-6.4%比-2.6%)。
本研究发现,在锡拉库萨省 COVID-19 大流行期间,常规儿童免疫接种的疫苗接种覆盖率受到负面影响。重要的是要制定一些追赶计划,以确保在大流行期间错过免疫接种的个人尽早进行接种。