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在职衰老?职业特征与加速生物衰老的关系。

Aging on the Job? The Association Between Occupational Characteristics and Accelerated Biological Aging.

机构信息

Leonard Davis School of Gerontology, University of Southern California, Los Angeles, California, USA.

出版信息

J Gerontol B Psychol Sci Soc Sci. 2023 Jun 26;78(7):1236-1245. doi: 10.1093/geronb/gbad055.

Abstract

OBJECTIVES

There is a common belief that demanding jobs can make workers age faster, but there is little empirical evidence linking occupational characteristics to accelerated biological aging. We examine how occupational categorizations and self-reported working conditions are associated with expanded biological age, which incorporates 22 biomarkers and captures physiologic dysregulation throughout several bodily systems.

METHODS

Data are from 1,133 participants in the Health and Retirement Study who were aged 51-60 and working for pay in the 2010 or 2012 wave and who participated in the 2016 Venous Blood Study. We estimate associations between occupational category (professional/managerial, sales/clerical, service, and manual) and self-reported working conditions (psychosocial demands, job control, heavy lifting, and working 55 or more hours per week) and expanded biological age.

RESULTS

Compared to same-age individuals working in professional or managerial positions, those working in service jobs appear 1.65 years older biologically even after adjusting for social and economic characteristics, self-reported working conditions, health insurance, and lifestyle-related risk factors. Low job control is associated with 1.40 years, heavy lifting with 2.08 years, and long working hours with 1.87 years of accelerated biological aging.

DISCUSSION

Adverse occupational characteristics held at midlife, particularly service work, low job control, heavy lifting, and long work hours, are associated with accelerated biological aging. These findings suggest that work may be important for the overall aging process beyond its associations with specific diseases or risk factors.

摘要

目的

有一种普遍的观点认为,高要求的工作会加速工人的衰老,但很少有实证证据将职业特征与加速的生物衰老联系起来。我们研究了职业分类和自我报告的工作条件如何与扩展的生物年龄相关联,扩展的生物年龄包含 22 种生物标志物,可捕捉到多个身体系统的生理失调。

方法

数据来自参加健康与退休研究的 1133 名年龄在 51-60 岁之间、在 2010 年或 2012 年调查期间有薪酬工作、并参加了 2016 年静脉血研究的参与者。我们估计职业类别(专业/管理、销售/文员、服务和体力劳动)和自我报告的工作条件(心理社会需求、工作控制、重物搬运和每周工作 55 小时或以上)与扩展的生物年龄之间的关联。

结果

与从事专业或管理工作的同年龄段个体相比,从事服务工作的个体在调整了社会经济特征、自我报告的工作条件、健康保险和与生活方式相关的风险因素后,其生物年龄看起来要老 1.65 岁。低工作控制与 1.40 年、重物搬运与 2.08 年、长时间工作与 1.87 年的加速生物衰老有关。

讨论

中年时的不利职业特征,特别是服务工作、低工作控制、重物搬运和长时间工作,与加速的生物衰老有关。这些发现表明,工作可能对整体衰老过程很重要,超出了其与特定疾病或风险因素的关联。

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