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退伍军人事务医疗中心中单用和双用阿片类药物使用者的阿片类药物使用和阿片类药物使用障碍。

Opioid use and opioid use disorder in mono and dual-system users of veteran affairs medical centers.

机构信息

VA Connecticut Healthcare System, West Haven, CT, United States.

Yale School of Medicine, New Haven, CT, United States.

出版信息

Front Public Health. 2023 Apr 4;11:1148189. doi: 10.3389/fpubh.2023.1148189. eCollection 2023.

Abstract

INTRODUCTION

Efforts to achieve opioid guideline concordant care may be undermined when patients access multiple opioid prescription sources. Limited data are available on the impact of dual-system sources of care on receipt of opioid medications.

OBJECTIVE

We examined whether dual-system use was associated with increased rates of new opioid prescriptions, continued opioid prescriptions and diagnoses of opioid use disorder (OUD). We hypothesized that dual-system use would be associated with increased odds for each outcome.

METHODS

This retrospective cohort study was conducted using Veterans Administration (VA) data from two facilities from 2015 to 2019, and included active patients, defined as Veterans who had at least one encounter in a calendar year (2015-2019). Dual-system use was defined as receipt of VA care as well as VA payment for community care (non-VA) services. Mono users were defined as those who only received VA services. There were 77,225 dual-system users, and 442,824 mono users. Outcomes were three binary measures: new opioid prescription, continued opioid prescription (i.e., received an additional opioid prescription), and OUD diagnosis (during the calendar year). We conducted a multivariate logistic regression accounting for the repeated observations on patient and intra-class correlations within patients.

RESULTS

Dual-system users were significantly younger than mono users, more likely to be women, and less likely to report white race. In adjusted models, dual-system users were significantly more likely to receive a new opioid prescription during the observation period [Odds ratio (OR) = 1.85, 95% confidence interval (CI) 1.76-1.93], continue prescriptions (OR = 1.24, CI 1.22-1.27), and to receive an OUD diagnosis (OR = 1.20, CI 1.14-1.27).

DISCUSSION

The prevalence of opioid prescriptions has been declining in the US healthcare systems including VA, yet the prevalence of OUD has not been declining at the same rate. One potential problem is that detailed notes from non-VA visits are not immediately available to VA clinicians, and information about VA care is not readily available to non-VA sources. One implication of our findings is that better health system coordination is needed. Even though care was paid for by the VA and presumably closely monitored, dual-system users were more likely to have new and continued opioid prescriptions.

摘要

简介

当患者从多个阿片类药物处方来源获取药物时,可能会破坏实现阿片类药物指南一致治疗的努力。关于双重系统治疗来源对阿片类药物使用的影响,数据有限。

目的

我们研究了双重系统使用是否与新的阿片类药物处方、继续使用阿片类药物处方和阿片类药物使用障碍(OUD)的诊断率增加有关。我们假设双重系统使用与每种结果的几率增加有关。

方法

这项回顾性队列研究使用了退伍军人事务部(VA)从 2015 年至 2019 年在两个设施的数据,纳入了活跃患者,定义为至少在一个日历年内(2015-2019 年)有过一次就诊的退伍军人。双重系统使用者被定义为接受 VA 护理以及 VA 支付社区护理(非 VA)服务。单一使用者被定义为仅接受 VA 服务的患者。共有 77225 名双重系统使用者和 442824 名单一使用者。结果是三个二进制测量值:新的阿片类药物处方、继续使用阿片类药物处方(即额外的阿片类药物处方)和 OUD 诊断(在日历年内)。我们进行了多变量逻辑回归,考虑了患者的重复观察和患者内的组内相关性。

结果

与单一使用者相比,双重系统使用者明显更年轻,更可能是女性,并且不太可能报告白人种族。在调整后的模型中,双重系统使用者在观察期内更有可能获得新的阿片类药物处方[优势比(OR)=1.85,95%置信区间(CI)1.76-1.93]、继续处方(OR=1.24,CI 1.22-1.27)和 OUD 诊断(OR=1.20,CI 1.14-1.27)。

讨论

美国医疗保健系统(包括 VA)的阿片类药物处方的流行率一直在下降,但 OUD 的流行率并没有以同样的速度下降。一个潜在的问题是,非 VA 就诊的详细记录不能立即提供给 VA 临床医生,而且 VA 护理的信息也不容易从非 VA 来源获得。我们研究结果的一个含义是需要更好的医疗系统协调。即使 VA 支付了治疗费用并进行了密切监测,但双重系统使用者更有可能获得新的和持续的阿片类药物处方。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ebd/10141670/d486abd648c4/fpubh-11-1148189-g001.jpg

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