冠状病毒性禽传染性支气管炎病毒的关键方面
Key Aspects of Coronavirus Avian Infectious Bronchitis Virus.
作者信息
Zhao Jing, Zhao Ye, Zhang Guozhong
机构信息
National Key Laboratory of Veterinary Public Health Security, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China.
Key Laboratory of Animal Epidemiology of the Ministry of Agriculture, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China.
出版信息
Pathogens. 2023 May 11;12(5):698. doi: 10.3390/pathogens12050698.
Infectious bronchitis virus (IBV) is an enveloped and positive-sense single-stranded RNA virus. IBV was the first coronavirus to be discovered and predominantly causes respiratory disease in commercial poultry worldwide. This review summarizes several important aspects of IBV, including epidemiology, genetic diversity, antigenic diversity, and multiple system disease caused by IBV as well as vaccination and antiviral strategies. Understanding these areas will provide insight into the mechanism of pathogenicity and immunoprotection of IBV and may improve prevention and control strategies for the disease.
传染性支气管炎病毒（IBV）是一种有包膜的正链单链RNA病毒。IBV是最早被发现的冠状病毒，主要在全球商业家禽中引起呼吸道疾病。本综述总结了IBV的几个重要方面，包括流行病学、遗传多样性、抗原多样性、由IBV引起的多系统疾病以及疫苗接种和抗病毒策略。了解这些领域将有助于深入了解IBV的致病性和免疫保护机制，并可能改善该疾病的预防和控制策略。
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