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临床治疗中有前景的RNA纳米技术:未来展望的叙述性综述

A promising RNA nanotechnology in clinical therapeutics: a future perspective narrative review.

作者信息

Tolba Mahmoud M, Jabbar Abdul, Afzal Sadia, Mahmoud Mohammed, Zulfiqar Farheen, El-Soudany Ingy, Samir Salma, Wadan Al-Hassan Soliman, Ellakwa Takwa E, Ellakwa Doha El-Sayed

机构信息

Pharmaceutical Division, Ministry of health & population, Faiyum, Egypt.

Department of Veterinary Medicine, Faculty of Veterinary Science, University of Veterinary & Animal Sciences, Lahore Punjab, Pakistan.

出版信息

Future Sci OA. 2023 Jul 18;9(8):FSO883. doi: 10.2144/fsoa-2023-0067. eCollection 2023 Sep.

Abstract

Nanotechnology is the use of materials that have unique nanoscale properties. In recent years, nanotechnologies have shown promising results for human health, especially in cancer treatment. The self-assembly characteristic of RNA is a powerful bottom-up approach to the design and creation of nanostructures through interdisciplinary biological, chemical and physical techniques. The use of RNA nanotechnology in therapeutics is about to be realized. This review discusses different kinds of nano-based drug delivery systems and their characteristic features.

摘要

纳米技术是指使用具有独特纳米级特性的材料。近年来,纳米技术在人类健康领域显示出了有前景的成果,尤其是在癌症治疗方面。RNA的自组装特性是一种强大的自下而上的方法,可通过跨学科的生物学、化学和物理技术来设计和创建纳米结构。RNA纳米技术在治疗学中的应用即将实现。本综述讨论了不同类型的基于纳米的药物递送系统及其特征。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d3c/10445585/6106ad50bdcd/fsoa-09-883-g1.jpg

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