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间充质干细胞在软组织再生医学中的应用:全面综述。

Mesenchymal Stem Cells in Soft Tissue Regenerative Medicine: A Comprehensive Review.

机构信息

Department of Experimental Medicine, University of Campania "Luigi Vanvitelli", Via L. Armanni 5, 80138 Naples, Italy.

Multidisciplinary Department of Medicine for Surgery and Orthodontics, University of Campania "Luigi Vanvitelli", Via L. Armanni 5, 80138 Naples, Italy.

出版信息

Medicina (Kaunas). 2023 Aug 10;59(8):1449. doi: 10.3390/medicina59081449.

Abstract

Soft tissue regeneration holds significant promise for addressing various clinical challenges, ranging from craniofacial and oral tissue defects to blood vessels, muscle, and fibrous tissue regeneration. Mesenchymal stem cells (MSCs) have emerged as a promising tool in regenerative medicine due to their unique characteristics and potential to differentiate into multiple cell lineages. This comprehensive review explores the role of MSCs in different aspects of soft tissue regeneration, including their application in craniofacial and oral soft tissue regeneration, nerve regeneration, blood vessel regeneration, muscle regeneration, and fibrous tissue regeneration. By examining the latest research findings and clinical advancements, this article aims to provide insights into the current state of MSC-based therapies in soft tissue regenerative medicine.

摘要

软组织再生在解决各种临床挑战方面具有重要意义,包括颅面和口腔组织缺陷以及血管、肌肉和纤维组织再生。间充质干细胞 (MSCs) 因其独特的特性和分化为多种细胞谱系的潜力,已成为再生医学中一种有前途的工具。本综述探讨了 MSCs 在软组织再生的不同方面的作用,包括它们在颅面和口腔软组织再生、神经再生、血管再生、肌肉再生和纤维组织再生中的应用。通过检查最新的研究发现和临床进展,本文旨在提供对基于 MSC 的软组织再生医学治疗方法的当前状态的深入了解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fbe6/10456353/93b3b335504e/medicina-59-01449-g001.jpg

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