功能表观基因组学：解开染色质复杂性之谜。
Functional epigenomics: chromatin complexity untangled.
机构信息
Department of Biology, Stanford University, Stanford, CA, USA.
出版信息
Nat Struct Mol Biol. 2023 Oct;30(10):1403-1405. doi: 10.1038/s41594-023-01088-3.
Abstract
The development of an epigenetics-focused, CRISPR-based high-content functional genomics screening platform provides insight into chromatin regulation and uncovers a potential strategy to treat an aggressive type of leukemia.
摘要
开发一个以表观遗传学为重点、基于 CRISPR 的高通量功能基因组学筛选平台，为染色质调控提供了深入了解，并揭示了一种治疗侵袭性白血病的潜在策略。
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