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比较袖状胃切除术与 Roux-en-Y 胃旁路术治疗老年(>60 岁)肥胖症患者的安全性和疗效:伞式系统评价和荟萃分析。

Comparing the safety and efficacy of sleeve gastrectomy versus Roux-en-Y gastric bypass in elderly (>60 years) with severe obesity: an umbrella systematic review and meta-analysis.

机构信息

Department of Surgery ,Minimally Invasive Surgery Research Center, Division of Minimally Invasive and Bariatric Surgery, Rasool-e Akram Hospital, School of Medicine, Iran University of Medical Sciences.

Center of Excellence of European Branch of International Federation for Surgery of Obesity, Hazrat_e Rasool Hospital, Tehran.

出版信息

Int J Surg. 2023 Nov 1;109(11):3541-3554. doi: 10.1097/JS9.0000000000000629.

Abstract

BACKGROUND

Today, bariatric surgeons face the challenge of treating older adults with class III obesity. The indications and outcomes of Roux-en-Y gastric bypass (RYGB) versus sleeve gastrectomy (SG) also constitute a controversy.

METHODS

PubMed, Web of Science and Scopus were searched to retrieve systematic reviews/meta-analyses published by 1 March 2022. The selected articles were qualitatively evaluated using A Measurement Tool to Assess systematic Reviews (AMSTAR).

RESULTS

An umbrella review included six meta-analyses retrieved from the literature. The risk of early-emerging and late-emerging complications decreased by 55% and 41% in the patients underwent SG than in those receiving RYGB, respectively. The chance of the remission of hypertension and obstructive sleep apnoea, respectively increased by 43% and 6%, but type-2 diabetes mellitus decreased by 4% in the patients underwent RYGB than in those receiving SG. RYGB also increased excess weight loss by 15.23% in the patients underwent RYGB than in those receiving SG.

CONCLUSION

Lower levels of mortality and early-emerging and late-emerging complications were observed in the older adults undergoing SG than in those receiving RYGB, which was, however, more efficient in term of weight loss outcomes and recurrence of obesity-related diseases.

摘要

背景

如今,肥胖症外科医生面临着治疗肥胖症 III 级的老年患者的挑战。胃旁路手术(RYGB)与袖状胃切除术(SG)的适应证和结果也存在争议。

方法

检索了 PubMed、Web of Science 和 Scopus,以获取截至 2022 年 3 月 1 日发表的系统评价/荟萃分析。使用评估系统评价的测量工具(AMSTAR)对选定的文章进行定性评估。

结果

伞式综述纳入了从文献中检索到的六项荟萃分析。与接受 RYGB 的患者相比,SG 患者的早期和晚期并发症风险分别降低了 55%和 41%。RYGB 患者高血压和阻塞性睡眠呼吸暂停的缓解几率分别增加了 43%和 6%,但 SG 患者的 2 型糖尿病则减少了 4%。RYGB 还使 RYGB 患者的超重减轻增加了 15.23%。

结论

与接受 RYGB 的患者相比,SG 患者的死亡率和早期及晚期并发症发生率较低,但在减肥效果和肥胖相关疾病的复发方面,RYGB 更有效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1f5/10651291/6d256e975867/js9-109-3541-g001.jpg

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