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长期暴露于户外空气污染与英国不同种族和出生国的全因全科医生就诊和住院之间的关联。

The association of long-term exposure to outdoor air pollution with all-cause GP visits and hospital admissions by ethnicity and country of birth in the United Kingdom.

机构信息

School of Geography and Sustainable Development, University of St Andrews, Scotland, United Kingdom.

出版信息

PLoS One. 2023 Oct 11;18(10):e0275414. doi: 10.1371/journal.pone.0275414. eCollection 2023.

Abstract

BACKGROUND

Air pollution is associated with poor health. Yet, more research is needed to reveal the association of long-term exposure to outdoor air pollution with less studied health outcomes like hospital admissions and general-practitioner (GP) visits and whether this association is stronger for ethnic minorities compared to the rest of population. This study investigates the association between air pollution and all-cause GP visits and hospital admissions by ethnicity in the United-Kingdom (UK).

METHODS

We used individual-level longitudinal data from the "UK Household Longitudinal Study" including 46,442 adult individuals who provided 140,466 responses across five years (2015-2019). This data was linked to yearly concentrations of NO2, SO2, and particulate-matter (PM10, PM2.5) outdoor pollution using the Lower Super Output Area (LSOA) of residence for each individual. Multilevel mixed-effects ordered logistic models were used to assess the association between air pollution and all-cause GP visits and hospital admissions.

RESULTS

We found higher odds of hospital admissions per 1 μg/m3 increase in annual concentrations of NO2 (OR = 1.008; 95%CI = 1.004-1.012), SO2 (OR = 1.048; 95%CI = 1.014-1.083), PM10 (OR = 1.011; 95%CI = 1.003-1.018), and PM2.5 (OR = 1.018; 95%CI = 1.007-1.029) pollutants. Higher odds of GP visits were also observed with increased exposure to NO2 (OR = 1.010; 95%CI = 1.006-1.014) and SO2 (OR = 1.114; 95%CI = 1.077-1.152) pollutants. The observed associations did not differ across ethnic groups, but by country of birth, they were more pronounced in individuals born outside UK than those born in UK.

CONCLUSION

This study supports an association between higher exposure to outdoor air pollution and increased all-cause hospital admissions and GP visits. Further longitudinal studies with longer follow-up time periods may be able to reveal more definite conclusions on the influence of ethnicity on the association between long-term outdoor air pollution and both hospital admissions and GP visits.

摘要

背景

空气污染与健康状况不佳有关。然而,需要更多的研究来揭示长期暴露于户外空气污染与较少研究的健康结果(如住院和全科医生就诊)之间的关联,以及这种关联在少数民族中是否比其他人群更强。本研究调查了英国(英国)不同种族之间空气污染与全因全科医生就诊和住院的关系。

方法

我们使用了来自“英国家庭纵向研究”的个体水平纵向数据,其中包括 46442 名成年人,他们在五年内(2015-2019 年)提供了 140466 次答复。该数据通过每个个体的居住的下超级区(LSOA)与每年的 NO2、SO2 和颗粒物(PM10、PM2.5)户外污染浓度相关联。使用多水平混合效应有序逻辑模型评估空气污染与全因全科医生就诊和住院之间的关联。

结果

我们发现,每年 NO2 浓度增加 1μg/m3,住院的几率增加(OR=1.008;95%CI=1.004-1.012),SO2(OR=1.048;95%CI=1.014-1.083),PM10(OR=1.011;95%CI=1.003-1.018)和 PM2.5(OR=1.018;95%CI=1.007-1.029)污染物。观察到的全科医生就诊几率也随着 NO2(OR=1.010;95%CI=1.006-1.014)和 SO2(OR=1.114;95%CI=1.077-1.152)污染物暴露的增加而增加。观察到的关联在不同种族群体中没有差异,但按出生国划分,在英国以外出生的个体比在英国出生的个体更为明显。

结论

本研究支持更高的户外空气污染暴露与全因住院和全科医生就诊增加之间的关联。具有更长随访时间的进一步纵向研究可能能够更明确地得出关于种族对长期户外空气污染与住院和全科医生就诊之间关联的影响的结论。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a53/10566689/1c8c4cdeb2ff/pone.0275414.g001.jpg

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