社论：宣布 COVID-19 大流行结束之际，推动 SARS-CoV-2 新变体出现、免疫逃逸和抗病毒治疗耐药性的因素
Editorial: Factors Driving New Variants of SARS-CoV-2, Immune Escape, and Resistance to Antiviral Treatments as the End of the COVID-19 Pandemic is Declared.
机构信息
Science Editor, Medical Science Monitor, International Scientific Information, Inc., Melville, NY, USA.
出版信息
Med Sci Monit. 2023 Nov 1;29:e942960. doi: 10.12659/MSM.942960.
On May 5, 2023, the Director-General of the World Health Organization (WHO) advised the transition to long-term management of the COVID-19 pandemic and that COVID-19 is now an established and ongoing health issue that is no longer a public health emergency of international concern (PHEIC). The WHO decision was based on an analysis of the decreasing trend in mortality, the decline in hospital admissions and Intensive Care Unit (ICU) admissions from COVID-19, and the increasing levels of population immunity to SARS-CoV-2. This Editorial aims to highlight what is known of the factors that drive new variants, subvariants, and lineages of SARS-CoV-2 associated with immune escape to previous infection or vaccines and resistance to antiviral treatments as the end of the COVID-19 pandemic is declared.
2023 年 5 月 5 日，世界卫生组织（世卫组织）总干事建议向 COVID-19 大流行的长期管理过渡，并称 COVID-19 现在是一个既定的持续存在的卫生问题，不再构成国际关注的突发公共卫生事件（PHEIC）。世卫组织的决定是基于对死亡率下降趋势、因 COVID-19 而住院和进入重症监护病房（ICU）人数减少以及人群对 SARS-CoV-2 的免疫力水平提高的分析。本社论旨在强调在宣布 COVID-19 大流行结束时，驱动 SARS-CoV-2 新变体、亚变体和谱系出现的因素，这些变体、亚变体和谱系与先前感染或疫苗产生的免疫逃逸以及对抗病毒治疗的耐药性有关。
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