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基线和治疗中出现的贝达喹啉耐药性在耐药性肺结核中的:系统评价和荟萃分析。

Baseline and treatment-emergent bedaquiline resistance in drug-resistant tuberculosis: a systematic review and meta-analysis.

机构信息

CAPRISA MRC-HIV-TB Pathogenesis and Treatment Research Unit, Centre for the AIDS Programme of Research in South Africa, Durban, South Africa

Division of Pulmonology and Critical Care, Department of Medicine, University of KwaZulu-Natal, Durban, South Africa.

出版信息

Eur Respir J. 2023 Dec 14;62(6). doi: 10.1183/13993003.00639-2023. Print 2023 Dec.

Abstract

Bedaquiline resistance is a major threat to drug-resistant tuberculosis control strategies. This analysis found a pooled prevalence of baseline bedaquiline resistance of 2.4% and a pooled prevalence of treatment-emergent bedaquiline resistance of 2.1%. https://bit.ly/3FC6yio

摘要

贝达喹啉耐药性是耐药结核病控制策略的主要威胁。本分析发现,基线时贝达喹啉耐药性的 pooled prevalence 为 2.4%,治疗中出现的贝达喹啉耐药性的 pooled prevalence 为 2.1%。https://bit.ly/3FC6yio

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