Suppr超能文献

年龄相关性听力损失的发病机制与治疗进展:文献综述

Pathogenesis and treatment progress in age-related hearing loss: a literature review.

作者信息

Yang Jianghui, Shao Zhangtao, Zhang Duomi, Wang Kai

机构信息

Health Science Center, Ningbo University Ningbo, Zhejiang, China.

出版信息

Int J Clin Exp Pathol. 2023 Nov 15;16(11):315-320. eCollection 2023.

Abstract

Age-related hearing loss (ARHL) is a progressive sensorineural hearing loss caused by age. The pathogenesis of ARHL is not completely clear at present, but it is closely related to auditory nerve degeneration, metabolic disorders, vitamin deficiency, and genetics, especially mitochondrial DNA damage. With the acceleration of industrialization and urbanization in our country, the impact of environmental noise is increasing, and ARHL has become one of the most important factors affecting the quality of life of the elderly in our country. Therefore, hearing intervention for patients with ARHL plays a crucial role in improving their quality of life. At present, the use of hearing aids and cochlear implants are the main means to treat the daily hearing difficulties and communication difficulties of patients with ARHL. However, in China, due to the economy, the concept of not wanting to treat the elderly, and other reasons, the hearing aid wearing rate compared to developed countries has significant differences. Cochlear implant is another option for patients with presbyacusis, and patients can obtain good hearing and speech recognition rate after surgery. At present, there is no definitive conclusion on whether the quality of life of patients after cochlear implantation has been improved, and this study will be reviewed based on previous relevant reports.

摘要

年龄相关性听力损失(ARHL)是一种由年龄引起的进行性感音神经性听力损失。目前,ARHL的发病机制尚不完全清楚,但它与听神经退变、代谢紊乱、维生素缺乏以及遗传学,尤其是线粒体DNA损伤密切相关。随着我国工业化和城市化进程的加快,环境噪声的影响日益增大,ARHL已成为影响我国老年人生活质量的最重要因素之一。因此,对ARHL患者进行听力干预对提高其生活质量起着至关重要的作用。目前,使用助听器和人工耳蜗是治疗ARHL患者日常听力困难和沟通困难的主要手段。然而,在我国,由于经济、不想治疗老年人的观念等原因,与发达国家相比,助听器佩戴率存在显著差异。人工耳蜗是老年聋患者的另一种选择,患者术后可获得良好的听力和言语识别率。目前,关于人工耳蜗植入术后患者生活质量是否得到改善尚无定论,本研究将基于以往相关报道进行综述。

相似文献

1
Pathogenesis and treatment progress in age-related hearing loss: a literature review.
Int J Clin Exp Pathol. 2023 Nov 15;16(11):315-320. eCollection 2023.
2
Biased auditory nerve central synaptopathy is associated with age-related hearing loss.
J Physiol. 2021 Mar;599(6):1833-1854. doi: 10.1113/JP281014. Epub 2021 Jan 31.
3
Compensation in neuro-system related to age-related hearing loss.
Acta Otolaryngol. 2024 Jan;144(1):30-34. doi: 10.1080/00016489.2023.2295400. Epub 2024 Jan 24.
4
Postlingually deaf adults of all ages derive equal benefits from unilateral multichannel cochlear implant.
J Am Acad Audiol. 2011 Nov-Dec;22(10):637-43. doi: 10.3766/jaaa.22.10.2.
5
Clinical Practice Guideline: Age-Related Hearing Loss Executive Summary.
Otolaryngol Head Neck Surg. 2024 May;170(5):1209-1227. doi: 10.1002/ohn.749.
6
Update on surgical and nonsurgical treatment options for age-related hearing loss.
Z Gerontol Geriatr. 2023 Jul;56(4):276-282. doi: 10.1007/s00391-023-02182-3. Epub 2023 Apr 6.
7
Auditory Perceptual Learning in Adults with and without Age-Related Hearing Loss.
Front Psychol. 2016 Feb 3;6:2066. doi: 10.3389/fpsyg.2015.02066. eCollection 2015.
8
Clinical Practice Guideline: Age-Related Hearing Loss.
Otolaryngol Head Neck Surg. 2024 May;170 Suppl 2:S1-S54. doi: 10.1002/ohn.750.
9
Primary Neural Degeneration in Noise-Exposed Human Cochleas: Correlations with Outer Hair Cell Loss and Word-Discrimination Scores.
J Neurosci. 2021 May 19;41(20):4439-4447. doi: 10.1523/JNEUROSCI.3238-20.2021. Epub 2021 Apr 21.

引用本文的文献

2
Mendelian randomization reveals the causal association between gout and hearing impairment in older adults.
Medicine (Baltimore). 2024 May 31;103(22):e38259. doi: 10.1097/MD.0000000000038259.

本文引用的文献

1
The Effect of Hearing Aid Use on the Association Between Hearing Loss and Brain Structure in Older Adults.
Ear Hear. 2022 May/Jun;43(3):933-940. doi: 10.1097/AUD.0000000000001148.
2
Cochlear implants in single-sided deaf recipients: Near normal higher-order processing.
Clin Neurophysiol. 2021 Feb;132(2):449-456. doi: 10.1016/j.clinph.2020.11.038. Epub 2020 Dec 29.
4
Hearing Loss in the Elderly.
Clin Geriatr Med. 2018 May;34(2):163-174. doi: 10.1016/j.cger.2018.01.001. Epub 2018 Feb 14.
6
Improvement of cognitive function after cochlear implantation in elderly patients.
JAMA Otolaryngol Head Neck Surg. 2015 May 1;141(5):442-50. doi: 10.1001/jamaoto.2015.129.
7
Is there an age limit for cochlear implantation?
Ann Otol Rhinol Laryngol. 2013 Apr;122(4):222-8. doi: 10.1177/000348941312200402.
8
Evaluation of antioxidant treatment in presbyacusis: prospective, placebo-controlled, double-blind, randomised trial.
J Laryngol Otol. 2013 Feb;127(2):134-41. doi: 10.1017/S0022215112003118. Epub 2013 Jan 15.
9
The role of mtDNA mutations in the pathogenesis of age-related hearing loss in mice carrying a mutator DNA polymerase gamma.
Neurobiol Aging. 2008 Jul;29(7):1080-92. doi: 10.1016/j.neurobiolaging.2007.01.014. Epub 2007 Mar 23.
10
[Mitochondrial DNA4568 deletions in guinea-pig associated with presbycusis].
Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2006 Dec;23(6):673-6.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验