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2023 年 9 月和 10 月,西班牙加利西亚在使用长效单克隆抗体预防婴儿呼吸道合胞病毒感染方面的初步经验。

Early lessons from the implementation of universal respiratory syncytial virus prophylaxis in infants with long-acting monoclonal antibodies, Galicia, Spain, September and October 2023.

机构信息

Genetics, Vaccines and Paediatric Infectious Diseases Research Group (GENVIP), Instituto de Investigación Sanitaria de Santiago (IDIS), Santiago de Compostela, Galicia, Spain.

Translational Paediatrics and Infectious Diseases, Hospital Clínico Universitario and University of Santiago de Compostela (USC), Santiago de Compostela, Spain.

出版信息

Euro Surveill. 2023 Dec;28(49). doi: 10.2807/1560-7917.ES.2023.28.49.2300606.

Abstract

A monoclonal antibody for universal respiratory syncytial virus prophylaxis in infants has recently been licensed. We share our experiences of integrating nirsevimab into the regional immunisation programme in Galicia, Spain. After a 3-week hospital-based immunisation campaign with flexible individualised appointments and educational activities, nirsevimab uptake was 97.5% in the high-risk group, 81.4% in the catch-up group and 92.6% in infants born during the campaign. This successful implementation strategy can serve as a model and may inform other countries' programmatic deliberations.

摘要

一种用于婴儿通用呼吸道合胞病毒预防的单克隆抗体最近已获得许可。我们分享了在西班牙加利西亚地区免疫规划中整合奈司替韦单抗的经验。在为期 3 周的基于医院的免疫接种活动中,采用灵活的个体化预约和教育活动,高风险组的奈司替韦单抗接种率为 97.5%,补种组为 81.4%,在活动期间出生的婴儿为 92.6%。这种成功的实施策略可以作为一种模式,并为其他国家的规划审议提供信息。

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