Department of Periodontology, Faculty of Dentistry, University of Oslo, Oslo, Norway.
Department of Periodontology, Institute of Odontology, The Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden.
Clin Oral Implants Res. 2024 Mar;35(3):321-329. doi: 10.1111/clr.14228. Epub 2023 Dec 19.
To evaluate long-term outcomes and prognostic factors of non-reconstructive surgical treatment of peri-implantitis.
One hundred forty-nine patients (267 implants) were surgically treated for peri-implantitis and followed for an average of 7.0 (SD: 3.6) years. The primary outcome was implant loss. Additional bone loss and surgical retreatment were secondary outcomes. Patient/implant characteristics, as well as clinical and radiographic parameters collected prior to initial surgery, were evaluated as potential predictors of implant loss. Flexible parametric survival models using restricted cubic spline functions were used; 5- and 10-year predicted rates of implant loss were calculated according to different scenarios.
Fifty-three implants (19.9%) in 35 patients (23.5%) were lost during the observation period. Implant loss occurred after a mean period of 4.4 (SD: 3.0) years and was predicted by implant surface characteristics (modified surface; HR 4.5), implant length (HR 0.8 by mm), suppuration at baseline (HR 2.7) and disease severity (baseline bone loss: HR 1.2 by mm). Estimates of 5- and 10-year implant loss ranged from 1% (best prognostic scenario; initial bone loss <40% of implant length, turned implant surface and absence of suppuration on probing (SoP)) to 63% (worst prognostic scenario; initial bone loss ≥60% of implant length, modified implant surface and SoP) and from 3% to 89%, respectively. Surgical retreatment was performed at 65 implants (24.3%) in 36 patients (24.2%) after a mean time period of 4.5 (3.1) years. In all, 59.5% of implants showed additional bone loss, were surgically retreated or lost.
Recurrence of disease is common following surgical treatment of peri-implantitis. The strongest predictor for implant loss was implant surface characteristics. Implant length as well as suppuration and disease severity at baseline were also relevant factors.
评估非重建性手术治疗种植体周围炎的长期疗效和预后因素。
对 149 例(267 枚种植体)种植体周围炎患者进行手术治疗,并平均随访 7.0(SD:3.6)年。主要结局为种植体丢失。次要结局为额外骨丢失和再次手术治疗。评估患者/种植体特征以及初始手术前收集的临床和影像学参数,作为种植体丢失的潜在预测因子。采用受限立方样条函数的灵活参数生存模型;根据不同情况计算 5 年和 10 年种植体丢失的预测率。
在观察期间,53 枚种植体(19.9%)在 35 名患者(23.5%)中丢失。种植体丢失发生在平均 4.4(SD:3.0)年后,种植体表面特征(改良表面;HR 4.5)、种植体长度(每毫米 HR 0.8)、基线时的化脓(HR 2.7)和疾病严重程度(基线骨丢失:每毫米 HR 1.2)是种植体丢失的预测因素。5 年和 10 年种植体丢失的估计值范围从 1%(最佳预后情况;初始骨丢失<种植体长的 40%,种植体表面转为改良型且探诊时无化脓(SoP))到 63%(最差预后情况;初始骨丢失≥种植体长的 60%,改良种植体表面和 SoP)和 3%至 89%。在平均 4.5(3.1)年后,对 36 名患者(24.2%)的 65 枚种植体(24.3%)进行了再次手术治疗。共有 59.5%的种植体出现了额外的骨丢失、再次手术治疗或丢失。
种植体周围炎手术后疾病复发较为常见。种植体表面特征是种植体丢失的最强预测因子。种植体长度以及基线时的化脓和疾病严重程度也是相关因素。