Suppr超能文献

打破RNA的常规模式——生命科学的“RNA复兴”

Breaking the mold with RNA-a "RNAissance" of life science.

作者信息

Jones Charles H, Androsavich John R, So Nina, Jenkins Matthew P, MacCormack Derek, Prigodich Andrew, Welch Verna, True Jane M, Dolsten Mikael

机构信息

Pfizer, 66 Hudson Boulevard, New York, NY, 10018, USA.

出版信息

NPJ Genom Med. 2024 Jan 9;9(1):2. doi: 10.1038/s41525-023-00387-4.

Abstract

In the past decade, RNA therapeutics have gone from being a promising concept to one of the most exciting frontiers in healthcare and pharmaceuticals. The field is now entering what many call a renaissance or "RNAissance" which is being fueled by advances in genetic engineering and delivery systems to take on more ambitious development efforts. However, this renaissance is occurring at an unprecedented pace, which will require a different way of thinking if the field is to live up to its full potential. Recognizing this need, this article will provide a forward-looking perspective on the field of RNA medical products and the potential long-term innovations and policy shifts enabled by this revolutionary and game-changing technological platform.

摘要

在过去十年中,RNA疗法已从一个充满前景的概念发展成为医疗保健和制药领域最令人兴奋的前沿领域之一。该领域目前正进入许多人所称的复兴时期,即“RNA复兴”,基因工程和递送系统的进步推动着这一复兴,使其能够开展更具雄心的研发工作。然而,这种复兴正以前所未有的速度发生,如果该领域要充分发挥其潜力,就需要一种不同的思维方式。认识到这一需求,本文将对RNA医疗产品领域以及这一革命性和改变游戏规则的技术平台可能带来的长期创新和政策转变提供前瞻性的视角。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/85d5/10776758/3596b961aa66/41525_2023_387_Fig1_HTML.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验