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2017-2020 年美国与国际旅行相关的多州非伤寒型和产志贺毒素大肠杆菌暴发。

Multistate nontyphoidal and Shiga toxin-producing outbreaks linked to international travel-United States, 2017-2020.

机构信息

Division of Foodborne, Waterborne and Environmental Diseases, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA.

Centers for Disease Control and Prevention, Epidemic Intelligence Service Program, Atlanta, GA, USA.

出版信息

Epidemiol Infect. 2024 Jan 11;152:e17. doi: 10.1017/S0950268823002017.

Abstract

Enteric bacterial infections are common among people who travel internationally. During 2017-2020, the Centers for Disease Control and Prevention investigated 41 multistate outbreaks of nontyphoidal and Shiga toxin-producing linked to international travel. Resistance to one or more antimicrobial agents was detected in at least 10% of isolates in 16 of 30 (53%) nontyphoidal outbreaks and 8 of 11 (73%) Shiga toxin-producing outbreaks evaluated by the National Antimicrobial Resistance Monitoring System. At least 10% of the isolates in 14 nontyphoidal outbreaks conferred resistance to one or more of the clinically significant antimicrobials used in human medicine. This report describes the epidemiology and antimicrobial resistance patterns of these travel-associated multistate outbreaks. Investigating illnesses among returned travellers and collaboration with international partners could result in the implementation of public health interventions to improve hygiene practices and food safety standards and to prevent illness and spread of multidrug-resistant organisms domestically and internationally.

摘要

肠细菌感染在国际旅行者中很常见。在 2017 年至 2020 年期间,疾病控制与预防中心调查了 41 起与国际旅行相关的非伤寒和产志贺毒素的多州暴发事件。在国家抗菌药物耐药性监测系统评估的 30 起非伤寒(53%)暴发事件和 11 起产志贺毒素(73%)暴发事件中,至少有 10%的分离株对一种或多种抗菌药物具有耐药性。在 14 起非伤寒暴发事件中,至少有 10%的分离株对一种或多种在人类医学中使用的具有临床意义的抗菌药物具有耐药性。本报告描述了这些与旅行相关的多州暴发事件的流行病学和抗菌药物耐药模式。对返回旅行者的疾病进行调查,并与国际合作伙伴合作,可能会实施公共卫生干预措施,以改善卫生习惯和食品安全标准,并防止多药耐药生物在国内和国际上的传播和疾病传播。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/638f/10894901/8639f2b8fbc2/S0950268823002017_fig1.jpg

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