Zhang Xinyu, Yin Tong, Wang Yincang, Du Jiazhe, Dou Jinjin, Zhang Xiwu
Graduate School, Heilongjiang University of Chinese Medicine, Harbin, China.
First Clinical Medical School, Heilongjiang University of Chinese Medicine, Harbin, China.
Front Pharmacol. 2024 Jan 8;14:1329969. doi: 10.3389/fphar.2023.1329969. eCollection 2023.
Cardiovascular diseases represent a significant worldwide problem, jeopardizing individuals' physical and mental wellbeing as well as their quality of life as a result of their widespread incidence and fatality. With the aging society, the occurrence of Cardiovascular diseases is progressively rising each year. However, although drugs developed for treating Cardiovascular diseases have clear targets and proven efficacy, they still carry certain toxic and side effect risks. Therefore, finding safe, effective, and practical treatment options is crucial. Scutellarin is the primary constituent of Erigeron breviscapus (Vant.) Hand-Mazz. This article aims to establish a theoretical foundation for the creation and use of secure, productive, and logical medications for Scutellarin in curing heart-related illnesses. Additionally, the examination and analysis of the signal pathway and its associated mechanisms with regard to the employment of SCU in treating heart diseases will impart innovative resolving concepts for the treatment and prevention of Cardiovascular diseases.
心血管疾病是一个全球性的重大问题,由于其广泛的发病率和死亡率,危及个人的身心健康以及生活质量。随着社会老龄化,心血管疾病的发生率逐年上升。然而,尽管用于治疗心血管疾病的药物有明确的靶点和已证实的疗效,但它们仍然存在一定的毒副作用风险。因此,寻找安全、有效和实用的治疗方案至关重要。灯盏花素是灯盏细辛的主要成分。本文旨在为灯盏花素在治疗心脏相关疾病方面创建和使用安全、有效和合理的药物奠定理论基础。此外,对灯盏花素治疗心脏病的信号通路及其相关机制进行研究和分析,将为心血管疾病的治疗和预防提供创新的解决思路。