Jiang Hongxin, Bu Lina
The College of Life Sciences, Northwest University, Xi'an, Shaanxi, China.
Department of Respiratory and Critical Care Medicine, Xi'an No.3 Hospital, The Affiliated Hospital of Northwest University, Xi'an, China.
Front Med (Lausanne). 2024 Jan 8;10:1323344. doi: 10.3389/fmed.2023.1323344. eCollection 2023.
Non-small cell lung cancer (NSCLC) overwhelmingly represents the predominant histological subtype of lung cancer, with lung adenocarcinoma emerging as the most prevalent form. Conventional Western medical treatments encompass a spectrum of modalities, including surgical interventions, cytotoxic chemotherapy, radiotherapy, targeted pharmacotherapy, and immunotherapy. In contrast, Traditional Chinese Medicine (TCM) methodologies encompass traditional Chinese medicine treatments, acupuncture therapies, and tuina treatments. While conventional Western medicine has made remarkable strides in the treatment of lung cancer, it is important to acknowledge the limitations inherent in singular treatment approaches. Consequently, the quest for a more comprehensive and integrative therapeutic paradigm becomes imperative. A deficiency of evaluation criteria specific to lung adenocarcinoma treatment in the realm of TCM represents an outstanding challenge in need of resolution. Nonetheless, in the backdrop of the continuous evolution of lung adenocarcinoma treatment modalities, the amalgamation of Chinese and Western medical approaches for treating this condition has exhibited a promising trajectory. It not only contributes to mitigating toxicity and augmenting efficacy but also serves to reduce a spectrum of postoperative complications, thereby enhancing the quality of patients' survival and extending life expectancy. This article furnishes a comprehensive survey of the research advancements in the integration of Chinese and Western medical approaches for treating lung adenocarcinoma. It elucidates the merits and demerits of individual and combined therapeutic strategies, surmounts current limitations, underscores the virtues of amalgamating Chinese and Western medical paradigms, and offers a more holistic, integrated, and efficacious treatment blueprint.
非小细胞肺癌(NSCLC)是肺癌最主要的组织学亚型,其中肺腺癌是最常见的形式。传统西医治疗方法包括一系列手段,如手术干预、细胞毒性化疗、放疗、靶向药物治疗和免疫治疗。相比之下,中医方法包括中药治疗、针灸疗法和推拿治疗。虽然西医在肺癌治疗方面取得了显著进展,但必须认识到单一治疗方法存在的局限性。因此,寻求更全面、综合的治疗模式势在必行。中医领域缺乏针对肺腺癌治疗的评估标准是一个亟待解决的突出挑战。尽管如此,在肺腺癌治疗模式不断演变的背景下,中西医结合治疗这种疾病已呈现出一条充满希望的轨迹。它不仅有助于减轻毒性、提高疗效,还能减少一系列术后并发症,从而提高患者的生存质量并延长预期寿命。本文全面综述了中西医结合治疗肺腺癌的研究进展。它阐明了个体和联合治疗策略的优缺点,克服了当前的局限性,强调了中西医结合模式的优点,并提供了一个更全面、综合、有效的治疗方案。