暴露于严重急性呼吸综合征冠状病毒 2（SARS-CoV-2）于濒危的伊比利亚猞猁（Lynx pardinus）中。

Exposure to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the endangered Iberian lynx (Lynx pardinus).

机构信息

Departamento de Sanidad Animal, Grupo de Investigación en Sanidad Animal y Zoonosis (GISAZ), UIC Zoonosis y Enfermedades Emergentes ENZOEM, Universidad de Córdoba, Córdoba, Spain; Grupo de Virología Clínica y Zoonosis, Unidad de Enfermedades Infecciosas, Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), Hospital Universitario Reina Sofía, Universidad de Córdoba, Córdoba, Spain; CIBERINFEC, ISCIII - CIBER de Enfermedades Infecciosas, Instituto de Salud Carlos III, 28029 Madrid, Spain.

出版信息

Vet Microbiol. 2024 Mar;290:110001. doi: 10.1016/j.vetmic.2024.110001. Epub 2024 Jan 17.

DOI:10.1016/j.vetmic.2024.110001

PMID:38280305

Abstract

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an emerging zoonotic virus of public and animal health concern, of which felids have been suggested as potential reservoirs. Although SARS-CoV-2 exposure has been detected in domestic and wild captive animals belonging to Felidae family, surveillance has not been carried out in free-ranging wild felids so far. The aim of the present study was to assess SARS-CoV-2 exposure in the Iberian lynx (Lynx pardinus), the most endangered felid in the world. Between 2019 and 2022, we conducted a seroepidemiological study of SARS-CoV-2 in 276 free-ranging and captive Iberian lynxes. Our results evidenced limited (0.4%; 95%CI: 0.0-1.1) but not negligible exposure to this emerging virus in this endangered felid species, increasing the SARS-CoV-2 host range. The circulation of this virus in wildlife evidences the need of integrated European wildlife monitoring.

摘要

严重急性呼吸综合征冠状病毒 2 (SARS-CoV-2) 是一种新兴的人畜共患病病毒，引起了公共卫生和动物卫生的关注，猫科动物被认为是潜在的病毒储存宿主。尽管在属于猫科的家养和野生圈养动物中已经检测到 SARS-CoV-2 的暴露，但迄今为止尚未对自由放养的野生猫科动物进行监测。本研究的目的是评估世界上最濒危的猫科动物——伊比利亚猞猁 (Lynx pardinus) 中 SARS-CoV-2 的暴露情况。在 2019 年至 2022 年期间，我们对 276 只自由放养和圈养的伊比利亚猞猁进行了 SARS-CoV-2 的血清流行病学研究。我们的研究结果表明，这种新兴病毒在这种濒危猫科动物中存在有限（0.4%；95%CI：0.0-1.1）但并非可以忽略不计的暴露，增加了 SARS-CoV-2 的宿主范围。这种病毒在野生动物中的传播表明需要进行欧洲野生动物的综合监测。