Department of Orthopaedics, Suzhou Hospital of Anhui Medical University, Suzhou, China.
Department of Laboratory, Bozhou People's Hospital, Bozhou, China.
Pain Physician. 2024 Feb;27(2):E255-E262.
Chronic low back pain (CLBP) is a significant health challenge with a high prevalence rate. Sleep disorders, which are prevalent among adults, have been linked with CLBP. However, the intricate relationship between sleep and pain adds complexity to our understanding of CLBP.
To investigate the association between CLBP and sleep disorders, with a focus on the potential role of sleep disorders as a risk factor for CLBP.
Cross-sectional study based on publicly available data from the National Health and Nutrition Examination Survey (NHANES) for one cycle (2009-2010).
The NHANES employs a complex, multistage probability sampling design to select a nationally representative sample.
In this study, we included patients aged 20 to 69 years from the NHANES 2009-2010 cycle. After eliminating cases with missing data, a total of 863 patients remained. Baseline characteristics were analyzed by stratifying patients based on their CLBP status to assess initial inter-group disparities. Due to age imbalances between groups, we employed a 1:1 propensity score matching (PSM) method, reducing the sample to 508 patients. The association between CLBP and trouble sleeping was investigated following this calibration using a multivariate logistic regression analysis.
Upon categorizing the baseline characteristics of 863 patients based on CLBP, we identified that those within the CLBP group tended to be older and had a greater prevalence of health conditions, including cancer, hypertension, and cardiovascular disease (CVD). Notably, the prevalence of sleep disorders was higher in the CLBP group than in the non-CLBP group (P < 0.001). After implementing an age-based PSM for the 2 groups, 508 patients were selected from the initial 863 patients. After adjusting for various confounders using multivariate logistic regression, our analysis revealed a strong association between sleep disorders and an increased risk of CLBP.
This is a cross-sectional study, and therefore causality cannot be established.
This study underscores the significant association between sleep disorders and an elevated risk of CLBP, highlighting the need for comprehensive management strategies that consider the role of sleep disorders in CLBP.
慢性下腰痛(CLBP)是一种发病率较高的重大健康挑战。睡眠障碍在成年人中很常见,与 CLBP 有关。然而,睡眠与疼痛之间复杂的关系增加了我们对 CLBP 的理解的复杂性。
探讨 CLBP 与睡眠障碍之间的关系,重点关注睡眠障碍作为 CLBP 风险因素的潜在作用。
基于国家健康和营养检查调查(NHANES)一个周期(2009-2010 年)的公开可用数据的横断面研究。
NHANES 采用复杂的多阶段概率抽样设计来选择具有全国代表性的样本。
在这项研究中,我们纳入了来自 NHANES 2009-2010 周期的 20 至 69 岁的患者。在消除缺失数据的病例后,共有 863 例患者留用。根据 CLBP 状态对患者进行分层,分析基线特征,以评估初始组间差异。由于组间年龄不平衡,我们采用了 1:1 倾向评分匹配(PSM)方法,将样本减少到 508 例患者。使用多变量逻辑回归分析在这种校准后调查 CLBP 与睡眠困难之间的关系。
根据 CLBP 将 863 例患者的基线特征进行分类,我们发现 CLBP 组的患者年龄较大,健康状况的患病率较高,包括癌症、高血压和心血管疾病(CVD)。值得注意的是,CLBP 组的睡眠障碍患病率高于非 CLBP 组(P <0.001)。对两组进行基于年龄的 PSM 后,从最初的 863 例患者中选择了 508 例患者。使用多变量逻辑回归调整各种混杂因素后,我们的分析表明睡眠障碍与 CLBP 风险增加之间存在很强的关联。
这是一项横断面研究,因此不能确定因果关系。
这项研究强调了睡眠障碍与 CLBP 风险增加之间的显著关联,突出了需要综合管理策略,考虑睡眠障碍在 CLBP 中的作用。