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眼、耳、喉区域以及鼻腔和口腔疾病的光动力疗法:综述

Photodynamic Therapy for Eye, Ear, Laryngeal Area, and Nasal and Oral Cavity Diseases: A Review.

作者信息

Domka Wojciech, Bartusik-Aebisher Dorota, Mytych Wiktoria, Myśliwiec Angelika, Dynarowicz Klaudia, Cieślar Grzegorz, Kawczyk-Krupka Aleksandra, Aebisher David

机构信息

Department of Otolaryngology, Medical College of The University of Rzeszów, 35-959 Rzeszów, Poland.

Department of Biochemistry and General Chemistry, Medical College of the University of Rzeszów, 35-959 Rzeszów, Poland.

出版信息

Cancers (Basel). 2024 Feb 2;16(3):645. doi: 10.3390/cancers16030645.

Abstract

Photodynamic therapy (PDT) has emerged as a promising modality for the treatment of various diseases. This non-invasive approach utilizes photosensitizing agents and light to selectively target and destroy abnormal cells, providing a valuable alternative to traditional treatments. Research studies have explored the application of PDT in different areas of the head. Research is focusing on a growing number of new developments and treatments for cancer. One of these methods is PDT. Photodynamic therapy is now a revolutionary, progressive method of cancer therapy. A very important feature of PDT is that cells cannot become immune to singlet oxygen. With this therapy, patients can avoid lengthy and costly surgeries. PDT therapy is referred to as a safe and highly selective therapy. These studies collectively highlight the potential of PDT as a valuable therapeutic option in treating the head area. As research in this field progresses, PDT may become increasingly integrated into the clinical management of these conditions, offering a balance between effectiveness and minimal invasiveness.

摘要

光动力疗法(PDT)已成为一种治疗各种疾病的有前景的方法。这种非侵入性方法利用光敏剂和光来选择性地靶向并破坏异常细胞,为传统治疗提供了一种有价值的替代方案。研究已经探索了PDT在头部不同区域的应用。研究正聚焦于越来越多针对癌症的新进展和治疗方法。其中一种方法就是PDT。光动力疗法现在是一种革命性、进步性的癌症治疗方法。PDT的一个非常重要的特点是细胞不会对单线态氧产生免疫。通过这种疗法,患者可以避免漫长且昂贵的手术。PDT疗法被称为一种安全且高度选择性的疗法。这些研究共同凸显了PDT作为治疗头部区域一种有价值治疗选择的潜力。随着该领域研究的进展,PDT可能会越来越多地融入这些病症的临床管理中,在有效性和最小侵入性之间实现平衡。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db53/10854993/c65ecc9911b2/cancers-16-00645-g001.jpg

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