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重新建立肥胖症患者的治疗结果和管理。

Outcomes and Management of Re-Establishing Bariatric Patients.

机构信息

Laboratory for Surgical and Metabolic Research, Brigham and Women's Hospital (Medhati, Saleh, Nimeri, Sheu, Tavakkoli), Brigham and Women's Hospital, Boston, MA.

From the Division of General and GI Surgery (Nimeri, Sheu, Tavakkoli), Brigham and Women's Hospital, Boston, MA.

出版信息

J Am Coll Surg. 2024 Jun 1;238(6):1035-1043. doi: 10.1097/XCS.0000000000001062. Epub 2024 Feb 29.

Abstract

BACKGROUND

Lifelong follow-up after metabolic and bariatric surgery (MBS) is necessary to monitor for patient outcomes and nutritional status. However, many patients do not routinely follow-up with their MBS team. We studied what prompted MBS patients to seek bariatric care after being lost to follow-up and the subsequent treatments they received.

STUDY DESIGN

A retrospective cohort study of patients after MBS who had discontinued regular MBS follow-up but represented to the MBS clinic between July 2018 and December 2022 to re-establish care. Patients with a history of a sleeve gastrectomy (SG), Roux-En-Y gastric bypass (RYGB), and adjustable gastric banding (AGB) were included.

RESULTS

We identified 400 patients (83.5% women, mean age 50.3 ± 12.2 years at the time of re-establishment of bariatric care), of whom 177 (44.3%) had RYGB, 154 (38.5%) had SG, and 69 (17.2%) had AGB. Overall, recurrent weight gain was the most common reason for presentation for all three procedures (81.2% in SG, 62.7% in RYGB, and 65.2% in AGB; p < 0.001). Patients who underwent SG were more likely to undergo a revision MBS compared with patients who underwent RYGB (16.9% vs 5.8%, p < 0.001), whereas patients who underwent RYGB were more likely to undergo an endoscopic intervention than patients who underwent SG (17.5% vs 7.8%, p < 0.001). The response to antiobesity medication agents, specifically glucagon-like peptide-1 receptor agonists drugs, was better in patients who underwent RYGB, than that in patients who underwent SG.

CONCLUSIONS

This study highlights recurrent weight gain as the most common reason for patients after MBS seeking to re-establish care with the MBS team. SG had a higher rate of revision MBS than RYGB, whereas endoscopic interventions were performed more frequently in the RYGB group. Antiobesity medication agents, especially glucagon-like peptide-1 receptor agonists drugs, were more effective in patients who underwent RYGB.

摘要

背景

代谢和减重手术(MBS)后的终身随访对于监测患者的结果和营养状况是必要的。然而,许多患者并没有定期与他们的 MBS 团队进行随访。我们研究了促使 MBS 患者在失去随访后寻求减重护理的原因,以及他们随后接受的治疗。

研究设计

这是一项对 MBS 后停止常规 MBS 随访但在 2018 年 7 月至 2022 年 12 月期间到 MBS 诊所重新建立护理的患者进行的回顾性队列研究。纳入有袖状胃切除术(SG)、Roux-en-Y 胃旁路术(RYGB)和可调胃束带术(AGB)病史的患者。

结果

我们确定了 400 名患者(83.5%为女性,重新建立减重护理时的平均年龄为 50.3±12.2 岁),其中 177 名(44.3%)接受了 RYGB,154 名(38.5%)接受了 SG,69 名(17.2%)接受了 AGB。总体而言,所有三种手术中最常见的就诊原因是体重再次增加(SG 为 81.2%,RYGB 为 62.7%,AGB 为 65.2%;p<0.001)。与接受 RYGB 的患者相比,接受 SG 的患者更有可能接受修订后的 MBS(16.9%比 5.8%,p<0.001),而接受 RYGB 的患者更有可能接受内镜干预,而不是 SG(17.5%比 7.8%,p<0.001)。与接受 SG 的患者相比,接受 RYGB 的患者对抗肥胖药物的反应更好,特别是胰高血糖素样肽-1 受体激动剂药物。

结论

这项研究强调,体重再次增加是 MBS 后患者寻求与 MBS 团队重新建立护理的最常见原因。SG 的修订 MBS 发生率高于 RYGB,而 RYGB 组更常进行内镜干预。抗肥胖药物,特别是胰高血糖素样肽-1 受体激动剂药物,在接受 RYGB 的患者中更有效。

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