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区域麻醉研究重点:一项国际德尔菲研究。

Research priorities in regional anaesthesia: an international Delphi study.

机构信息

Department of Anaesthesia, Aneurin Bevan University Health Board, Newport, South Wales, UK.

Department of Anaesthesia & Perioperative Medicine, Guy's and St Thomas' NHS Foundation Trust, London, UK; Centre for Human and Applied Physiological Sciences, King's College London, London, UK.

出版信息

Br J Anaesth. 2024 May;132(5):1041-1048. doi: 10.1016/j.bja.2024.01.033. Epub 2024 Mar 5.

Abstract

BACKGROUND

Regional anaesthesia use is growing worldwide, and there is an increasing emphasis on research in regional anaesthesia to improve patient outcomes. However, priorities for future study remain unclear. We therefore conducted an international research prioritisation exercise, setting the agenda for future investigators and funding bodies.

METHODS

We invited members of specialist regional anaesthesia societies from six continents to propose research questions that they felt were unanswered. These were consolidated into representative indicative questions, and a literature review was undertaken to determine if any indicative questions were already answered by published work. Unanswered indicative questions entered a three-round modified Delphi process, whereby 29 experts in regional anaesthesia (representing all participating specialist societies) rated each indicative question for inclusion on a final high priority shortlist. If ≥75% of participants rated an indicative question as 'definitely' include in any round, it was accepted. Indicative questions rated as 'definitely' or 'probably' by <50% of participants in any round were excluded. Retained indicative questions were further ranked based on the rating score in the final Delphi round. The final research priorities were ratified by the Delphi expert group.

RESULTS

There were 1318 responses from 516 people in the initial survey, from which 71 indicative questions were formed, of which 68 entered the modified Delphi process. Eleven 'highest priority' research questions were short listed, covering themes of pain management; training and assessment; clinical practice and efficacy; technology and equipment.

CONCLUSIONS

We prioritised unanswered research questions in regional anaesthesia. These will inform a coordinated global research strategy for regional anaesthesia and direct investigators to address high-priority areas.

摘要

背景

区域麻醉的应用在全球范围内不断增加,对区域麻醉的研究也越来越重视,以改善患者的治疗效果。然而,未来研究的重点尚不清楚。因此,我们进行了一项国际性的研究优先级设定工作,为未来的研究人员和资助机构设定了议程。

方法

我们邀请了来自六大洲的专业区域麻醉学会成员提出他们认为尚未得到解答的研究问题。这些问题被整合为具有代表性的指示性问题,并进行了文献回顾,以确定是否有任何指示性问题已经被已发表的工作所回答。未得到解答的指示性问题进入了三轮修改后的德尔菲法流程,在该流程中,29 名区域麻醉专家(代表所有参与的专业学会)对每个指示性问题进行了评估,以确定其是否应被列入最终的高优先级短名单。如果≥75%的参与者在任何一轮中都将某个指示性问题评为“绝对”包括在内,则该问题将被接受。如果在任何一轮中,<50%的参与者将某个指示性问题评为“绝对”或“可能”包括在内,则该问题将被排除。保留的指示性问题将根据最后一轮德尔菲法的评分进一步排名。最终的研究重点由德尔菲专家组批准。

结果

初始调查收到了来自 516 人的 1318 份回复,从中形成了 71 个指示性问题,其中 68 个进入了修改后的德尔菲法流程。有 11 个“最高优先级”的研究问题被列入短名单,涵盖了疼痛管理、培训和评估、临床实践和疗效、技术和设备等主题。

结论

我们确定了区域麻醉中未解答的研究问题。这些问题将为区域麻醉的协调全球研究策略提供信息,并指导研究人员解决高优先级领域的问题。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/68e7/11103078/50f70ac026af/gr1.jpg

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