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某些皮肤病中的锌、铜和铁。

Zinc, Copper, and Iron in Selected Skin Diseases.

机构信息

Department of Aesthetic Medicine, Medical University of Bialystok, 15-267 Bialystok, Poland.

Department of Bromatology, Medical University of Bialystok, 15-222 Bialystok, Poland.

出版信息

Int J Mol Sci. 2024 Mar 29;25(7):3823. doi: 10.3390/ijms25073823.

Abstract

Trace elements are essential for maintaining the body's homeostasis, and their special role has been demonstrated in skin physiology. Among the most important trace elements are zinc, copper, and iron. A deficiency or excess of trace elements can be associated with an increased risk of skin diseases, so increasing their supplementation or limiting intake can be helpful in dermatological treatment. In addition, determinations of their levels in various types of biological material can be useful as additional tests in dermatological treatment. This paper describes the role of these elements in skin physiology and summarizes data on zinc, copper, and iron in the course of selected, following skin diseases: , , , and . In addition, this work identifies the potential of trace elements as auxiliary tests in dermatology. According to preliminary studies, abnormal levels of zinc, copper, and iron are observed in many skin diseases and their determinations in serum or hair can be used as auxiliary and prognostic tests in the course of various dermatoses. However, since data for some conditions are conflicting, clearly defining the potential of trace elements as auxiliary tests or elements requiring restriction/supplement requires further research.

摘要

微量元素对于维持身体的内稳态至关重要,其在皮肤生理学中的特殊作用已经得到证实。最重要的微量元素包括锌、铜和铁。微量元素的缺乏或过量可能与皮肤病风险增加有关,因此增加其补充或限制摄入可能有助于皮肤病的治疗。此外,测定各种类型生物材料中的这些元素水平可作为皮肤病治疗中的附加检查。本文描述了这些元素在皮肤生理学中的作用,并总结了锌、铜和铁在以下几种选定皮肤疾病中的数据:痤疮、酒渣鼻、特应性皮炎、银屑病和斑秃。此外,这项工作还确定了微量元素作为皮肤病学辅助检查的潜力。根据初步研究,在许多皮肤病中观察到锌、铜和铁的水平异常,其在血清或头发中的测定可作为各种皮肤病过程中的辅助和预后检查。然而,由于某些情况下的数据存在矛盾,因此明确将微量元素作为辅助检查或需要限制/补充的元素的潜力需要进一步研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/58e4/11011755/4f055e5c9e37/ijms-25-03823-g001.jpg

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