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欧洲泌尿外科学会泌尿感染指南:2024 年指南摘要。

European Association of Urology Guidelines on Urological Infections: Summary of the 2024 Guidelines.

机构信息

Department of Urology and Pediatric Urology, RWTH Aachen University, Aachen, Germany; Department of Urology and Kidney Transplantation, Martin-Luther-University, Halle, Germany.

Department of Translational Research and New Technologies, University of Pisa, Pisa, Italy.

出版信息

Eur Urol. 2024 Jul;86(1):27-41. doi: 10.1016/j.eururo.2024.03.035. Epub 2024 May 6.

Abstract

BACKGROUND AND OBJECTIVE

Urological infections significantly impact the wellbeing and quality of life of individuals owing to their widespread occurrence and diverse clinical manifestations. The objective of the guidelines panel was to provide evidence-based guidance on the diagnosis, treatment, and prevention of urinary tract infections (UTIs) and male accessory-gland infections, while addressing crucial public health aspects related to infection control and antimicrobial stewardship.

METHODS

For the 2024 guidelines on urological infections, new and relevant evidence was identified, collated, and appraised via a structured assessment of the literature. Databases searched included Medline, EMBASE, and the Cochrane Libraries. Recommendations within the guidelines were developed by the panel to prioritise clinically important care decisions. The strength of each recommendation was determined according to a balance between desirable and undesirable consequences of alternative management strategies, the quality of the evidence (including the certainty of estimates), and the nature and variability of patient values and preferences.

KEY FINDINGS AND LIMITATIONS

Key recommendations emphasise the importance of a thorough medical history and physical examination for patients with urological infections. The guidelines stress the role of antimicrobial stewardship to combat the rising threat of antimicrobial resistance, providing recommendations for antibiotic selection, dosing, and duration on the basis of the latest evidence.

CONCLUSIONS AND CLINICAL IMPLICATIONS

This overview of the 2024 EAU guidelines offers valuable insights into managing urological infections and are designed for effective integration into clinical practice.

PATIENT SUMMARY

The European Association of Urology has issued an updated guideline on urological infections. The guidelines provide recommendations for diagnosis, treatment, and prevention, with a particular focus on minimising antibiotic use because of the increasing global threat of antimicrobial resistance.

摘要

背景与目的

由于泌尿系统感染的广泛发生和多样化临床表现,它们显著影响个体的健康和生活质量。本指南专家组的目标是提供基于证据的泌尿系统感染和男性附属腺体感染的诊断、治疗和预防指南,同时解决与感染控制和抗菌药物管理相关的重要公共卫生问题。

方法

针对 2024 年泌尿系统感染指南,通过对文献进行结构化评估,确定并综合了新的相关证据。检索的数据库包括 Medline、EMBASE 和 Cochrane 图书馆。指南中的推荐意见由专家组制定,旨在优先考虑具有重要临床意义的护理决策。根据替代管理策略的理想和不良后果之间的平衡、证据质量(包括估计的确定性)以及患者价值观和偏好的性质和可变性,确定了每个推荐意见的强度。

主要发现和局限性

关键推荐意见强调了对泌尿系统感染患者进行详细病史采集和体格检查的重要性。指南强调了抗菌药物管理的作用,以应对抗菌药物耐药性不断上升的威胁,根据最新证据提供了抗生素选择、剂量和疗程的建议。

结论和临床意义

本指南概述提供了管理泌尿系统感染的宝贵见解,旨在有效融入临床实践。

患者总结

欧洲泌尿外科学会发布了泌尿系统感染的更新指南。该指南提供了诊断、治疗和预防的建议,特别强调了减少抗生素使用的重要性,因为全球对抗菌药物耐药性的威胁日益增加。

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