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治疗寻求的 AUD 患者的奖励、缓解和习惯饮酒特征。

Reward, relief, and habit drinking profiles in treatment seeking individuals with an AUD.

机构信息

Department of Psychology, University of California, Los Angeles, Los Angeles, California 90095, United States.

Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, Los Angeles, California 90095, United States.

出版信息

Alcohol Alcohol. 2024 Mar 16;59(3). doi: 10.1093/alcalc/agae032.

Abstract

AIMS

This study aimed to compare reward, relief, and habit treatment-seeking individuals on recent drinking, alcohol use disorder (AUD) phenomenology, and mood. The second aim of the study was to evaluate the predictive validity of reward, relief, and habit profiles.

METHOD

Treatment-seeking individuals with an AUD (n = 169) were recruited to participate in a medication trial for AUD (NCT03594435). Reward, relief, and habit drinking groups were assessed using the UCLA Reward Relief Habit Drinking Scale. Group differences at baseline were evaluated using univariate analyses of variance. A subset of participants were enrolled in a 12-week, double-blind, placebo-controlled medication trial (n = 102), and provided longitudinal drinking and phenomenology data. The predictive validity of group membership was assessed using linear regression analyses.

RESULTS

At baseline, individuals who drink primarily for relief had higher craving and negative mood than those who drink for reward and habit. Prospectively, membership in the relief drinking group predicted greater alcohol use, greater heavy drinking, and fewer days abstinent compared to those in the reward drinking group. Membership in the relief drinking group also predicted greater alcohol craving, more alcohol-related consequences, and more anxiety symptoms over 12 weeks compared to those in the reward drinking group.

CONCLUSIONS

This study provides support for reward and relief drinking motive profiles in treatment-seeking individuals with an AUD. Membership in the relief drinking motive group was predictive of poorer drinking outcomes and more negative symptomology over 12 weeks, indicating that individuals who drink for relief may be a particularly vulnerable sub-population of individuals with AUD.

摘要

目的

本研究旨在比较奖励寻求者、缓解寻求者和习惯寻求者在近期饮酒、酒精使用障碍(AUD)表现和情绪方面的差异。本研究的第二个目的是评估奖励、缓解和习惯特征的预测效度。

方法

招募有 AUD 的治疗寻求者(n=169)参加 AUD 的药物试验(NCT03594435)。使用 UCLA 奖励缓解习惯饮酒量表评估奖励、缓解和习惯饮酒组。使用单变量方差分析评估基线时的组间差异。一部分参与者参加了为期 12 周的双盲、安慰剂对照药物试验(n=102),并提供了纵向饮酒和表现的数据。使用线性回归分析评估组内成员身份的预测效度。

结果

基线时,主要为缓解而饮酒的个体比因奖励和习惯而饮酒的个体有更高的渴望和负面情绪。前瞻性地,与奖励饮酒组相比,缓解饮酒组的成员与更大的饮酒量、更多的重度饮酒和更少的戒酒天数有关。与奖励饮酒组相比,缓解饮酒组的成员也预测了更大的酒精渴望、更多的酒精相关后果和更多的焦虑症状在 12 周内。

结论

这项研究为 AUD 治疗寻求者中的奖励和缓解饮酒动机特征提供了支持。缓解饮酒动机组的成员与 12 周内更差的饮酒结果和更多的负面症状有关,这表明因缓解而饮酒的个体可能是 AUD 个体中特别脆弱的亚人群。

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