Department of Molecular Biology, University of California at San Diego, San Diego, California, USA.
Microb Physiol. 2024;34(1):142-152. doi: 10.1159/000540068. Epub 2024 Jul 2.
We propose that intermittent fasting (time-restricted eating), in agreement with the conclusions of other biologists, as revealed in recent publications, promotes the achievement of numerous health benefits including the extension of human and animal lifespans. Background: There is evidence, obtained both with animal model systems and with humans, that intermittent fasting has health benefits. These benefits include extended longevity, weight loss, and counteracting various disease conditions. Such procedures positively influence the benefits of human tissue-specific microbiomes and minimize the consequences of organellar apoptosis. Key Messages: In this review, we attempt to summarize the predominant evidence, published in the scientific literature, relevant to the conclusions that in general, and in many specific instances, intermittent fasting has long-term benefits to animals, including humans, with respect to overall and specific organismal health and longevity.
我们提出,间歇性禁食(限时进食)符合其他生物学家的结论,正如最近的出版物所揭示的那样,它可以促进许多健康益处的实现,包括延长人类和动物的寿命。背景:有证据表明,间歇性禁食对动物模型系统和人类都有健康益处。这些益处包括延长寿命、减肥和对抗各种疾病状况。这些措施积极影响人类组织特异性微生物组的益处,并最大限度地减少细胞器凋亡的后果。关键信息:在这篇综述中,我们试图总结发表在科学文献中的主要证据,这些证据与以下结论有关:一般来说,间歇性禁食对包括人类在内的动物有长期益处,就整体和特定的机体健康和寿命而言。