人类细胞对辐射的关键分子DNA损伤反应。
Key molecular DNA damage responses of human cells to radiation.
作者信息
Zhang Chencheng, Liu Jibin, Wu Jun, Ranjan Kamakshi, Cui Xiaopeng, Wang Xingdan, Zhang Dianzheng, Zhu Shudong
机构信息
Cancer Research Center, Nantong Tumor Hospital, Nantong, China.
Cancer Research Institute, The Affiliated Tumor Hospital of Nantong University, Nantong, China.
出版信息
Front Cell Dev Biol. 2024 Jul 10;12:1422520. doi: 10.3389/fcell.2024.1422520. eCollection 2024.
Our understanding of the DNA damage responses of human cells to radiation has increased remarkably over the recent years although some notable signaling events remain to be discovered. Here we provide a brief account of the key molecular events of the responses to reflect the current understanding of the key underlying mechanisms involved.
尽管仍有一些值得注意的信号事件有待发现，但近年来我们对人类细胞对辐射的DNA损伤反应的理解有了显著提高。在此，我们简要介绍这些反应的关键分子事件，以反映目前对所涉及的关键潜在机制的理解。
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