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癌症相关性神经性疼痛:当前的指南是什么?

Neuropathic Pain in Cancer: What Are the Current Guidelines?

机构信息

Leeds Institute of Health Sciences, School of Medicine, Faculty of Medicine and Health, University of Leeds Level, 10 Worsley Building, Clarendon Road, Leeds, LS2 9LN, UK.

Academic Unit of Palliative Care, St Gemma's Hospice, Leeds, UK.

出版信息

Curr Treat Options Oncol. 2024 Sep;25(9):1193-1202. doi: 10.1007/s11864-024-01248-7. Epub 2024 Aug 5.

Abstract

Neuropathic cancer pain is experienced by 30-40% of patients with cancer. It significantly reduces quality of life and overall wellbeing for patients living with and beyond cancer. The underlying mechanisms of neuropathic pain in patients with cancer are complex and involve direct tumour involvement, nerve compression or infiltration, chemotherapy and/or radiotherapy-induced nerve damage, or post-surgical complications. It is crucial for healthcare professionals to assess and manage neuropathic cancer pain effectively. There is increasing recognition that standardisation of neuropathic pain assessment leads to tailored management and improved patient outcomes. Pain management strategies, including medication, interventional analgesia, physical and complementary therapy, can help alleviate neuropathic pain and improve the patient's comfort and quality of life.

摘要

神经病理性癌痛在 30-40%的癌症患者中出现。它显著降低了癌症患者及其康复者的生活质量和整体幸福感。癌症患者神经病理性疼痛的潜在机制很复杂,涉及到直接的肿瘤累及、神经压迫或浸润、化疗和/或放疗引起的神经损伤,或手术后并发症。医疗保健专业人员有效地评估和管理神经病理性癌痛至关重要。越来越多的人认识到,神经病理性疼痛评估的标准化可导致量身定制的管理和改善患者的结局。疼痛管理策略,包括药物治疗、介入性镇痛、物理和补充治疗,可以帮助缓解神经病理性疼痛,提高患者的舒适度和生活质量。

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