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苏丹东部孕妇铁叶酸补充剂依从性的患病率及相关因素:一项横断面研究

Prevalence and Factors Associated with Adherence to Iron-Folic Acid Supplementation Among Pregnant Women in Eastern Sudan: A Cross-Sectional Study.

作者信息

Saeed Mustafa S, Adam Gamal K, Hussein Samah M, AlHabardi Nadiah, Adam Ishag

机构信息

Department of Pharmacy Practice, College of Pharmacy, Qassim University, Buraidah, Qassim, 51452, Saudi Arabia.

Faculty of Medicine, Gadarif University, Gadarif, Sudan.

出版信息

Patient Prefer Adherence. 2024 Aug 6;18:1665-1674. doi: 10.2147/PPA.S476738. eCollection 2024.

Abstract

PURPOSE

The present study was conducted to determine the prevalence and factors associated with adherence to iron-folic acid supplementation (IFAS) among pregnant women in eastern Sudan.

METHODS

A cross-sectional survey was conducted among pregnant women who obtained antenatal care (ANC) at Gadarif Maternal Hospital in eastern Sudan between May 1 and August 31, 2023. Face-to-face interview questionnaires were used to gather sociodemographic, obstetric, and clinical data (age, parity, education, residence, and previous medical diseases). Knowledge of anemia and IFAS was assessed. Multivariate analysis was performed to adjust for confounders.

RESULTS

A total of 568 pregnant women were enrolled in the present study. Among them, 449 (79.0%) adhered to the IFAS. The multivariate analysis showed that the adjusted odds ratio (AOR) of IFAS adherence increased with ANC visits > 4 (AOR = 1.68, 95.0% CI = 1.01-2.77) and knowledge of anemia (AOR = 2.06, 95.0% CI = 1.437-3.276). In the univariate analysis, maternal occupation and knowledge of IFAS adherence were the only factors associated with IFAS adherence. Maternal age, parity, gestational age, education, residence, occupation, medical insurance, medical disease, and husband's occupation were not associated with IFAS. Forgetfulness (71.0%), frustration from taking many drugs (54.6%), and unpleasant tests of the supplement (50.7%) were the main reasons for not taking the IFAS.

CONCLUSION

About four out of five pregnant women adhered to the IFAS, indicating a good level of adherence, especially among women who attended more than four ANC visits and those with good knowledge of anemia. More attention is needed to encourage ANC to increase adherence to IFAS.

摘要

目的

本研究旨在确定苏丹东部孕妇中铁叶酸补充剂(IFAS)依从性的患病率及相关因素。

方法

于2023年5月1日至8月31日期间,在苏丹东部加达里夫妇产医院接受产前护理(ANC)的孕妇中进行了一项横断面调查。采用面对面访谈问卷收集社会人口统计学、产科和临床数据(年龄、产次、教育程度、居住地和既往病史)。评估了贫血和IFAS的知识。进行多变量分析以调整混杂因素。

结果

本研究共纳入568名孕妇。其中,449名(79.0%)坚持服用IFAS。多变量分析显示,ANC就诊次数>4次时IFAS依从性的调整优势比(AOR)增加(AOR = 1.68,95.0%可信区间[CI] = 1.01 - 2.77),以及贫血知识(AOR = 2.06,95.0% CI = 1.437 - 3.276)。在单变量分析中,母亲职业和IFAS依从性知识是与IFAS依从性相关的唯一因素。母亲年龄、产次、孕周、教育程度、居住地、职业、医疗保险、疾病和丈夫职业与IFAS无关。忘记(71.0%)、服用多种药物带来的困扰(54.6%)以及补充剂令人不适的味道(50.7%)是未服用IFAS的主要原因。

结论

约五分之四的孕妇坚持服用IFAS,表明依从性良好,尤其是在接受四次以上ANC就诊的妇女和贫血知识良好的妇女中。需要更多关注以鼓励ANC提高对IFAS的依从性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b1e/11317201/d1efd3e98158/PPA-18-1665-g0001.jpg

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