Division of Birth Defects and Infant Disorders, National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, 4770 Buford Highway, Mailstop S106-3, Atlanta, GA 30341, United States; US Public Health Service Commissioned Corps, 1101 Wootton Parkway, Rockville, MD 20852, United States.
Office of the Director, National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, 4770 Buford Highway, Atlanta, GA 30341, United States.
Drug Alcohol Depend. 2024 Oct 1;263:112420. doi: 10.1016/j.drugalcdep.2024.112420. Epub 2024 Aug 23.
Fetal alcohol spectrum disorders (FASDs) are lifelong conditions that can occur in a person with prenatal alcohol exposure. Although studies using intensive, in-person assessments of children in selected communities have found higher estimates of children with FASDs than studies of healthcare claims data, claims-based studies provide more current information about individuals with recognized FASDs from diverse populations. We estimated the proportion of children with administratively reported FASDs in two large healthcare claims databases.
We analyzed Merative™ MarketScan® commercial and Medicaid claims databases, that include nationwide data from employer-sponsored health plans and from Medicaid programs in 8-10 states, respectively. For each database, we estimated the proportion of children aged 0-17 years with administratively reported FASDs, identified by one inpatient or two outpatient codes for prenatal alcohol exposure or fetal alcohol syndrome during the entire seven-year period from 2015 to 2021 and during each year.
During 2015-2021, 1.2 per 10,000 commercially-insured and 6.1 per 10,000 Medicaid-insured children had an administratively reported FASD; estimates varied by sex, geography, and other available demographics. Among commercially-insured children, 0.5 per 10,000 in 2015 and 0.6 per 10,000 children in 2021 had an administratively reported FASD; among Medicaid-insured, 1.2 per 10,000 in 2015 and 2.1 per 10,000 children in 2021 had an administratively reported FASD.
Although an underestimate of the true population of children with FASDs, patterns in administratively reported FASDs by demographics were consistent with previous studies. Healthcare claims studies can provide timely, ongoing information about children with recognized FASDs to complement in-persons studies.
胎儿酒精谱系障碍(FASD)是一种终身疾病,可由胎儿期酒精暴露引起。尽管使用在选定社区中对儿童进行密集、面对面评估的研究发现,患有 FASD 的儿童的估计数高于医疗保健索赔数据研究,但基于索赔的研究提供了更多来自不同人群的经认可的 FASD 个体的最新信息。我们评估了两个大型医疗保健索赔数据库中报告的患有 FASD 的儿童比例。
我们分析了 Merative MarketScan 商业和医疗补助索赔数据库,这些数据库分别包含全国性雇主赞助的健康计划数据和 8-10 个州的医疗补助计划数据。对于每个数据库,我们根据在整个 2015 年至 2021 年的七年期间和每年报告的一次住院或两次门诊编码,为产前酒精暴露或胎儿酒精综合征确定的行政报告的 0-17 岁儿童中患有 FASD 的比例进行了估计。
在 2015-2021 年期间,商业保险的儿童中有 1.2/10000 人,医疗补助保险的儿童中有 6.1/10000 人行政报告患有 FASD;估计值因性别、地理位置和其他可用人口统计学特征而异。在商业保险的儿童中,2015 年为 0.5/10000,2021 年为 0.6/10000 患有行政报告的 FASD;在医疗补助保险的儿童中,2015 年为 1.2/10000,2021 年为 2.1/10000 患有行政报告的 FASD。
尽管这是对患有 FASD 的儿童真实人数的低估,但人口统计学上行政报告的 FASD 模式与之前的研究一致。医疗保健索赔研究可以提供有关经认可的 FASD 儿童的及时、持续信息,以补充面对面研究。