Center for Regenerative Medicine, Abigail Wexner Research Institute, Nationwide Children's Hospital, Columbus, OH, USA.
College of Medicine, The Ohio State University, Columbus, OH, USA.
Eur Respir Rev. 2024 Sep 18;33(173). doi: 10.1183/16000617.0073-2024. Print 2024 Jul.
Pulmonary mucociliary clearance (MCC) is an important defence mechanism of the respiratory system and clears pathogens and foreign particles from the airways. Understanding the effect of disease states, drugs, toxins and airway manipulations on MCC could be beneficial in preventing early pulmonary disease and developing new pulmonary therapeutics. This review summarises the current methods and future efforts to detect pulmonary MCC .
肺部黏液纤毛清除(MCC)是呼吸系统的重要防御机制,可清除气道中的病原体和外来颗粒。了解疾病状态、药物、毒素和气道操作对 MCC 的影响,有助于预防早期肺部疾病和开发新的肺部治疗方法。本文总结了目前检测肺部 MCC 的方法和未来的努力。