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大麻二酚治疗颈椎病相关性疼痛:一例报告

Cannabidiol for the Treatment of Cervical Spondyloarthritis-Related Pain: A Case Report.

作者信息

Tadei Valdecir C

机构信息

Anesthesiology, Faculdade de Medicina de São José do Rio Preto, São José do Rio Preto, BRA.

出版信息

Cureus. 2024 Aug 19;16(8):e67224. doi: 10.7759/cureus.67224. eCollection 2024 Aug.

Abstract

Spondyloarthritis (SA) is a chronic inflammatory disease that predominantly affects the spinal column. SA-related pain can be intense, persistent, and disabling. Studies with cannabis have been conducted involving patients with refractory epilepsy, multiple sclerosis, Parkinson's disease, sleep disorders, and chronic pain. Cannabidiol is the major non-psychotropic component of cannabis, has anti-inflammatory and analgesic properties, and exerts anxiolytic and mood-stabilizing effects. This paper reports a case of a 72-year-old male with SA, with mild stenoses of the spinal canal at C4-C5 and C5-C6 and stenoses of the left neural foramina at C3-C4, C4-C5, C5-C6, and C6-C7. The use of cannabidiol in our patient achieved satisfactory results in the control of pain related to cervical spondyloarthritis.

摘要

脊柱关节炎(SA)是一种主要影响脊柱的慢性炎症性疾病。SA相关的疼痛可能剧烈、持续且使人致残。已经对患有难治性癫痫、多发性硬化症、帕金森病、睡眠障碍和慢性疼痛的患者进行了大麻相关研究。大麻二酚是大麻的主要非精神活性成分,具有抗炎和镇痛特性,并具有抗焦虑和稳定情绪的作用。本文报告了一例72岁男性SA患者,其C4 - C5和C5 - C6水平存在轻度椎管狭窄,C3 - C4、C4 - C5、C5 - C6和C6 - C7水平存在左侧神经孔狭窄。在我们的患者中使用大麻二酚在控制与颈椎脊柱关节炎相关的疼痛方面取得了满意的效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2fdd/11410304/f0d309c92b46/cureus-0016-00000067224-i01.jpg

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