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寻找美丽与健康:女性衰老、营养与端粒的秘密

Searching for Beauty and Health: Aging in Women, Nutrition, and the Secret in Telomeres.

机构信息

Division of Gerontology and Geriatrics, Department of Medicine and Surgery, University of Perugia, 06123 Perugia, Italy.

Department of Medicine, Academy of Applied Medical and Social Sciences, Lotnicza 2, 82-300 Elblag, Poland.

出版信息

Nutrients. 2024 Sep 15;16(18):3111. doi: 10.3390/nu16183111.

Abstract

Women typically outlive men, yet they often experience greater frailty and a higher incidence of chronic diseases as they age. By exploring the biological foundations of aging, with a particular focus on telomere dynamics, this manuscript aims to describe how dietary and lifestyle choices can significantly influence the aging process. The review comprehensively examines current research, underscoring the power of nutrition to counteract age-related changes, support healthy aging, and maintain vitality and beauty in women. The exploration of telomeres-the protective caps at the ends of chromosomes-reveals how they serve as markers of cellular aging and are potential targets for interventions aimed at enhancing women's longevity and quality of life. This study also emphasizes the importance of sex-specific approaches and precision medicine in understanding the unique health challenges women face as they age. By proposing targeted strategies, the review seeks to address these challenges, offering insights into preventive measures that can foster resilience, promote well-being, and extend healthy life expectancy in women. Ultimately, this work provides a sophisticated understanding of the aging process in women, highlighting the pivotal role of tailored interventions in preserving both health and beauty.

摘要

女性的寿命通常比男性长,但随着年龄的增长,她们往往更容易体弱多病,慢性病的发病率也更高。本研究通过探讨衰老的生物学基础,特别是端粒动力学,旨在描述饮食和生活方式选择如何显著影响衰老过程。该综述全面审查了当前的研究,强调了营养在对抗与年龄相关的变化、支持健康衰老以及维持女性活力和美丽方面的强大作用。对端粒(染色体末端的保护帽)的探索揭示了它们如何作为细胞衰老的标志物,以及它们作为干预措施的潜在靶点,旨在提高女性的寿命和生活质量。本研究还强调了采用性别特异性方法和精准医学来理解女性在衰老过程中面临的独特健康挑战的重要性。通过提出有针对性的策略,该综述旨在解决这些挑战,提供关于预防措施的见解,以促进女性的韧性、幸福感,并延长健康预期寿命。总的来说,这项工作深入了解了女性的衰老过程,强调了量身定制的干预措施在维持健康和美丽方面的关键作用。

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