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苦木素类化合物作为有前景的抗癌药物。

Quassinoids as Promising Anti-cancer Agents.

作者信息

Mishra Tripti, Banik Bimal Krishna

机构信息

Centre of Innovative and Applied Bioprocessing (CIAB), Sector-81, Knowledge City, Mohali, Punjab, India.

School of Advanced Chemical Sciences, Shoolini University of Biotechnology and Management Sciences, Solan, Himachal Pradesh, India.

出版信息

Curr Med Chem. 2025;32(26):5433-5473. doi: 10.2174/0109298673313760240911160930.

Abstract

The use of current anticancer drugs is hampered by significant side effects and high costs. In the pursuit of safer, more effective, and affordable options, researchers have turned to nature as a valuable source of potential anticancer compounds. Quassinoids, a class of natural terpenoids, have garnered attention for their anticancer properties. This comprehensive review aims to shed light on natural quassinoids and their anticancer effects, offering valuable insights for researchers dedicated to the development of novel anticancer therapeutics.

摘要

目前抗癌药物的使用受到严重副作用和高成本的阻碍。为了寻求更安全、更有效且更经济实惠的选择,研究人员将目光投向了大自然,将其视为潜在抗癌化合物的宝贵来源。苦木素类化合物作为一类天然萜类化合物,因其抗癌特性而备受关注。这篇综述旨在阐明天然苦木素类化合物及其抗癌作用,为致力于开发新型抗癌疗法的研究人员提供有价值的见解。

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