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体内真空等离子体表面处理后牙种植体的骨结合

Osseointegration of Dental Implants after Vacuum Plasma Surface Treatment In Vivo.

作者信息

Kahm Se Hoon, Lee Sang Hwa, Lim Youbong, Jeon Hyun Jeong, Yun Kyoung-In

机构信息

Department of Dentistry, Eunpyeong St. Mary's Hospital, College of Medicine, The Catholic University of Korea, 1021, Tongil-ro, Eunpyeong-gu, Seoul 03312, Republic of Korea.

Plasmapp Co., Ltd., 9, Giheungdanji-ro 24beon-gil, Giheung-gu, Yongin-si 17086, Republic of Korea.

出版信息

J Funct Biomater. 2024 Sep 24;15(10):278. doi: 10.3390/jfb15100278.

Abstract

Previous studies have highlighted the need for post-treatment of implants due to surface aging. This study investigated the effect of vacuum plasma (VP) treatment on the osseointegration of sandblasted, large grit, acid-etched (SLA) implant surfaces. The hypothesis was that VP might enhance implant stability, measured by implant stability quotient (ISQ) and histological osseointegration through bone-to-implant contact (BIC) and bone area ratio (BA) in rabbit models. Eighteen implants were either untreated or treated with VP and installed into the femurs of six rabbits, which were sacrificed after four weeks. Histological analyses of BIC and BA, along with micro-CT analysis of bone volume and ISQ, were performed. The VP-treated group showed higher levels of BA, bone volume, and ISQ, but no statistically significant differences were observed between the control and experimental groups. Despite limitations, both groups achieved better osseointegration and regeneration, warranting further studies on plasma treatment effects over varying implantation periods.

摘要

以往的研究强调了由于表面老化对植入物进行后处理的必要性。本研究调查了真空等离子体(VP)处理对喷砂、大颗粒、酸蚀(SLA)植入物表面骨整合的影响。假设是VP可能会增强植入物稳定性,通过植入物稳定性商数(ISQ)来衡量,并通过兔模型中的骨与植入物接触(BIC)和骨面积比(BA)进行组织学骨整合评估。18枚植入物要么未处理,要么用VP处理,然后植入6只兔子的股骨中,4周后将兔子处死。进行了BIC和BA的组织学分析,以及骨体积和ISQ的显微CT分析。VP处理组的BA、骨体积和ISQ水平较高,但对照组和实验组之间未观察到统计学上的显著差异。尽管存在局限性,但两组均实现了更好的骨整合和再生,这需要对不同植入期的等离子体处理效果进行进一步研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c53a/11508880/302824b4c71d/jfb-15-00278-g001.jpg

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