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用于选择性检测次氯酸根离子、生物成像以及制备用于合成取代咪唑的氧化亚铁纳米颗粒的氮掺杂碳量子点。

N-doped carbon quantum dots for the selective detection of OCl ions, bioimaging, and the production of FeO nanoparticles utilized in the synthesis of substituted imidazole.

作者信息

Hota Namrata Priyadarshini, Kulathu Iyer Sathiyanarayanan

机构信息

Department of Chemistry, School of Advanced Sciences, Vellore Institute of Technology Vellore-632 014 India

出版信息

RSC Adv. 2024 Nov 6;14(48):35448-35459. doi: 10.1039/d4ra06474g. eCollection 2024 Nov 4.

Abstract

Nitrogen-doped quantum dots (NCQD) were synthesized by solvothermal means using -phenylenediamine and l-tartaric acid. The resultant NCQD produced a high quantum yield (40.3%) and a vivid green fluorescence. They were about 6 nm in size. The NCQD is useful in HeLa cell bioimaging investigations and is used for the fluorescence detection of OCl ions. The quantum dots' Limit of Detection (LoD) was discovered to be 40 nM. Additionally, cytotoxicity testing was conducted, and we found out that HeLa cells safely endured up to 6.5 mg ml of NCQD. Furthermore, NCQDs were employed to synthesize FeO nanoparticles, with the quantum dots acting as a reducing and stabilizing agent. The nanoparticles exhibited remarkable catalytic activity towards organic processes due to their size of 11 nm and surface area of 67.360 m g. Excellent yields of tri-substituted imidazole derivatives were produced using FeO nanoparticles as nanocatalysts in a solvent-free method.

摘要

采用对苯二胺和L-酒石酸通过溶剂热法合成了氮掺杂量子点(NCQD)。所得的NCQD具有高量子产率(40.3%)和鲜艳的绿色荧光。它们的尺寸约为6纳米。NCQD可用于HeLa细胞生物成像研究,并用于OCl离子的荧光检测。发现量子点的检测限(LoD)为40 nM。此外,进行了细胞毒性测试,我们发现HeLa细胞能够安全耐受高达6.5 mg/ml的NCQD。此外,NCQDs被用于合成FeO纳米颗粒,量子点充当还原剂和稳定剂。由于其尺寸为11纳米,表面积为67.360 m²/g,这些纳米颗粒对有机反应表现出显著的催化活性。使用FeO纳米颗粒作为纳米催化剂,通过无溶剂方法制备了高产率的三取代咪唑衍生物。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0987/11538961/3f473b284dd4/d4ra06474g-f1.jpg

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