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Amplifying cancer immunity: AMPK activators and gammadelta T cells unveiled.

作者信息

Anwar Firoz, Al-Abbasi Fahad A, Almalki Naif Abdullaha R, Alhayyani Sultan, Verma Amita, Kumar Vikas

机构信息

Department of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia.

Experimental Biochemistry Unit, King Fahad Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia.

出版信息

EXCLI J. 2024 Oct 29;23:1327-1329. doi: 10.17179/excli2024-7784. eCollection 2024.

Abstract
摘要

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本文引用的文献

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Arming Vδ2 T Cells with Chimeric Antigen Receptors to Combat Cancer.
Clin Cancer Res. 2024 Aug 1;30(15):3105-3116. doi: 10.1158/1078-0432.CCR-23-3495.
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Advancements in γδT cell engineering: paving the way for enhanced cancer immunotherapy.
Front Immunol. 2024 Mar 21;15:1360237. doi: 10.3389/fimmu.2024.1360237. eCollection 2024.
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Phosphoantigens glue butyrophilin 3A1 and 2A1 to activate Vγ9Vδ2 T cells.
Nature. 2023 Sep;621(7980):840-848. doi: 10.1038/s41586-023-06525-3. Epub 2023 Sep 6.
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CRISPR screens decode cancer cell pathways that trigger γδ T cell detection.
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The emerging roles of γδ T cells in cancer immunotherapy.
Nat Rev Clin Oncol. 2023 Mar;20(3):178-191. doi: 10.1038/s41571-022-00722-1. Epub 2023 Jan 9.
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Targeting Options of Tumor-Associated Macrophages (TAM) Activity in Gliomas.
Curr Neuropharmacol. 2023;21(3):457-470. doi: 10.2174/1570159X20666220120120203.
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Butyrophilin 2A1 is essential for phosphoantigen reactivity by γδ T cells.
Science. 2020 Feb 7;367(6478). doi: 10.1126/science.aay5516. Epub 2020 Jan 9.
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Translating gammadelta (γδ) T cells and their receptors into cancer cell therapies.
Nat Rev Drug Discov. 2020 Mar;19(3):169-184. doi: 10.1038/s41573-019-0038-z. Epub 2019 Sep 6.
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Targeting AMPK: From Ancient Drugs to New Small-Molecule Activators.
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