Wolf Susan M, Pruett Timothy L, McVan Claire Colby, Brister Evelyn, Callier Shawneequa L, Capron Alexander M, Childress James F, Goodwin Michele Bratcher, Hyun Insoo, Isasi Rosario, Maynard Andrew D, Oye Kenneth A, Thompson Paul B, Tiersch Terrence R
UNIVERSITY OF MINNESOTA, MINNEAPOLIS, MINNESOTA, USA.
ROCHESTER INSTITUTE OF TECHNOLOGY, ROCHESTER, NEW YORK, USA.
J Law Med Ethics. 2024;52(3):534-552. doi: 10.1017/jme.2024.129. Epub 2024 Dec 16.
Advanced biopreservation technologies using subzero approaches such as supercooling, partial freezing, and vitrification with reanimating techniques including nanoparticle infusion and laser rewarming are rapidly emerging as technologies with potential to radically disrupt biomedicine, research, aquaculture, and conservation. These technologies could pause biological time and facilitate large-scale banking of biomedical products including organs, tissues, and cell therapies.
采用过冷、部分冷冻和玻璃化等零下方法的先进生物保存技术,以及包括纳米颗粒注入和激光复温在内的复苏技术,正迅速成为有可能从根本上颠覆生物医学、研究、水产养殖和保护领域的技术。这些技术可以暂停生物时间,并促进包括器官、组织和细胞疗法在内的生物医学产品的大规模储存。