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中度颗粒物暴露会增加前列腺癌风险:一项全国性纵向队列研究(2010 - 2020年)

Moderate PM exposure increases prostate cancer: a longitudinal nationwide cohort study (2010-2020).

作者信息

Rho Mi Jung, Park Yong Hyun, Park Jihwan

机构信息

College of Health Science, Dankook University, Cheonan-si, Chungcheongnam-do, Republic of Korea.

Department of Urology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.

出版信息

Front Public Health. 2025 Jan 10;12:1490458. doi: 10.3389/fpubh.2024.1490458. eCollection 2024.

Abstract

INTRODUCTION

Fine dust exposure has been reported to affect patients with prostate cancer, making it crucial to understand how environmental pollutants impact health. This study aimed to determine the risk of prostate cancer in South Korea associated with moderate levels of fine dust (PM) exposure.

METHODS

We analyzed data from 20,430 individuals in the National Health Insurance Sharing Service database from 2010 to 2020, comparing a new prostate cancer group ( = 4,071, 19.9%) with a non-prostate cancer group ( = 16,359, 80.1%). Using PM data from Air Korea's annual average air quality database, we conducted logistic regression analysis to assess the risk of prostate cancer.

RESULTS

Our findings indicate that even moderate PM exposure is a risk factor for developing prostate cancer. Additionally, even at low levels of PM, moderate PM exposure significantly impacts prostate cancer development, with lifestyle ha bits potentially lowering this risk.

DISCUSSION

These results underscore the need for stricter environmental standards for PM and proactive policies to reduce public health and long-term social costs. Public awareness, including mask use and air quality management, is essential.

摘要

引言

据报道,接触细颗粒物会影响前列腺癌患者,因此了解环境污染物如何影响健康至关重要。本研究旨在确定韩国中度接触细颗粒物(PM)与前列腺癌风险之间的关系。

方法

我们分析了2010年至2020年国家健康保险共享服务数据库中20430人的数据,将新的前列腺癌组(n = 4071,19.9%)与非前列腺癌组(n = 16359,80.1%)进行比较。利用韩国空气年度平均空气质量数据库中的PM数据,我们进行了逻辑回归分析,以评估前列腺癌风险。

结果

我们的研究结果表明,即使是中度接触PM也是患前列腺癌的一个风险因素。此外,即使在低水平的PM环境下,中度接触PM也会显著影响前列腺癌的发展,生活方式习惯可能会降低这种风险。

讨论

这些结果强调了对PM制定更严格环境标准以及采取积极政策以降低公共卫生和长期社会成本的必要性。公众意识,包括佩戴口罩和空气质量管理,至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6296/11759305/461d5b8cc907/fpubh-12-1490458-g0001.jpg

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