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皮肤癌管理的临床方法:黑色素瘤患者诊断、治疗及预后的当前进展综述

Clinical Approaches for the Management of Skin Cancer: A Review of Current Progress in Diagnosis, Treatment, and Prognosis for Patients with Melanoma.

作者信息

Connor Colton, Carr Quinton L, Sweazy Alisa, McMasters Kelly, Hao Hongying

机构信息

School of Medicine, University of Louisville, Louisville, KY 40202, USA.

The Hiram C. Polk, Jr., MD Department of Surgery, School of Medicine, University of Louisville, Louisville, KY 40202, USA.

出版信息

Cancers (Basel). 2025 Feb 19;17(4):707. doi: 10.3390/cancers17040707.

Abstract

Melanoma represents a significant public health challenge due to its increasing incidence and potential for metastasis. This review will explore the current clinical approaches to the management of melanoma, focusing on advancements in diagnosis, treatment, and prognosis. Methods for early detection and accurate staging have been enhanced by new diagnostic strategies. Treatment modalities have expanded beyond traditional surgical excision to include targeted therapy and immunotherapy. Prognostic assessment has benefited from the development of novel biomarkers and genetic profiling. This review will highlight the progress made in the multidisciplinary management of melanoma, underscoring the importance of continuous research to improve patient outcomes.

摘要

由于黑色素瘤发病率不断上升且有转移的可能性,它对公共卫生构成了重大挑战。本综述将探讨黑色素瘤管理的当前临床方法,重点关注诊断、治疗和预后方面的进展。新的诊断策略增强了早期检测和准确分期的方法。治疗方式已从传统的手术切除扩展到包括靶向治疗和免疫治疗。预后评估受益于新型生物标志物和基因图谱的发展。本综述将强调黑色素瘤多学科管理取得的进展,强调持续研究对改善患者预后的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f60/11853469/cf6af494389b/cancers-17-00707-g001.jpg

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