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2005年至2018年中国北京抑郁症住院患者2型糖尿病的患病率及危险因素

Prevalence and Risk Factors of Type 2 Diabetes Mellitus among Depression Inpatients from 2005 to 2018 in Beijing, China.

作者信息

Gao Peng, Yang Fude, Ma Qiuyue, Ma Botao, Jing Wenzhan, Liu Jue, Guo Moning, Li Juan, Wang Zhiren, Liu Min

机构信息

Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing, China.

Beijing Huilongguan Hospital, Peking University Huilonguan Clinical Medical School, Beijing, China.

出版信息

Health Data Sci. 2025 Mar 5;5:0111. doi: 10.34133/hds.0111. eCollection 2025.

Abstract

There are few data on the comorbidity of diabetes in Chinese patients with depression. We aimed to calculate the prevalence and explore risk factors of type 2 diabetes mellitus (T2DM) among depression inpatients from 2005 to 2018 in Beijing. This study is a cross-sectional study. The data collected from 19 specialized psychiatric hospitals in Beijing were analyzed. The prevalence of T2DM and its distribution were analyzed. The multivariable logistic regression was performed to explore the risk factors of T2DM. A total of 20,899 depression inpatients were included. The prevalence of T2DM was 9.13% [95% confidence interval (CI), 8.74% to 9.52%]. The prevalence of T2DM showed an upward trend with year ( for trend < 0.001) and age ( for trend < 0.001). The prevalence of T2DM was higher among readmitted patients (12.97%) and patients with comorbid hypertension (26.16%), hyperlipidemia (21.28%), and nonalcoholic fatty liver disease (NAFLD) (18.85%). The prevalence of T2DM in females was lower than in males among patients aged 18 to 59 years, while the prevalence of T2DM in females was higher than in males among patients aged ≥60 years. T2DM was associated with older age [adjusted odds ratios (aORs) ranged from 3.68 to 29.95, < 0.001], hypertension (aOR, 3.01; 95% CI, 2.70 to 3.35; < 0.001), hyperlipidemia (aOR, 1.69; 95% CI, 1.50 to 1.91; < 0.001), and NAFLD (aOR, 1.58; 95% CI, 1.37 to 1.82; < 0.001). The prevalence of T2DM among depression inpatients from 2005 to 2018 in Beijing was high and increased with the year. Depression inpatients who were older and with hypertension, hyperlipidemia, and NAFLD had a higher prevalence and risk of T2DM.

摘要

关于中国抑郁症患者中糖尿病共病的数据较少。我们旨在计算2005年至2018年北京抑郁症住院患者中2型糖尿病(T2DM)的患病率,并探索其危险因素。本研究为横断面研究。对从北京19家专业精神病医院收集的数据进行分析。分析T2DM的患病率及其分布情况。采用多变量逻辑回归分析探索T2DM的危险因素。共纳入20899例抑郁症住院患者。T2DM的患病率为9.13%[95%置信区间(CI),8.74%至9.52%]。T2DM的患病率随年份(趋势<0.001)和年龄(趋势<0.001)呈上升趋势。再次入院患者(12.97%)以及合并高血压(26.16%)、高脂血症(21.28%)和非酒精性脂肪性肝病(NAFLD)(18.85%)的患者中T2DM的患病率更高。在18至59岁的患者中,女性T2DM的患病率低于男性,而在≥60岁的患者中,女性T2DM的患病率高于男性。T2DM与年龄较大[调整后的优势比(aORs)范围为3.68至29.95,<0.001]、高血压(aOR,3.01;95%CI,2.70至3.35;<0.001)、高脂血症(aOR,1.69;95%CI,1.50至1.91;<0.001)和NAFLD(aOR,1.58;95%CI,1.37至1.82;<0.001)相关。2005年至2018年北京抑郁症住院患者中T2DM的患病率较高,且随年份增加。年龄较大以及合并高血压、高脂血症和NAFLD的抑郁症住院患者T2DM的患病率和风险更高。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3179/11880573/eb03cd9884cd/hds.0111.fig.001.jpg

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