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固态发酵谷物:酚类物质增加及其在减轻肝脏疾病中的作用

Solid-State Fermented Cereals: Increased Phenolics and Their Role in Attenuating Liver Diseases.

作者信息

Wijaya Ganesha Yanuar Arief, Vornoli Andrea, Giambastiani Lucia, Digiacomo Maria, Macchia Marco, Szymczak Bartłomiej, Wójcik Marta, Pozzo Luisa, Longo Vincenzo

机构信息

Doctoral School in Life Sciences, University of Siena, 53100 Siena, Italy.

Department of Pharmacy, University of Pisa, Via Bonanno, 56126 Pisa, Italy.

出版信息

Nutrients. 2025 Mar 4;17(5):900. doi: 10.3390/nu17050900.

Abstract

Liver diseases, a leading cause of global mortality, necessitate effective dietary strategies. Fermented cereals, traditionally recognized for benefits in glucose regulation, lipid profiles, and antioxidant activity, hold potential for managing conditions such as type 2 diabetes, hypertension, and obesity. However, their specific impact on liver health requires further investigation. Fermentation, particularly solid-state fermentation (SSF), enhances the bioavailability of beneficial compounds, including phenolics. This review summarizes recent studies on the phenolic content of fermented cereals, highlighting variations based on microbial strains and cereal types. It examines the hepatoprotective effects of these phenolics, drawing on and research. Furthermore, the review explores recent findings on the impact of fermented cereals on liver health and related diseases. This work provides a foundation for future research exploring fermented cereals as a dietary intervention for liver disease prevention and management.

摘要

肝脏疾病是全球死亡的主要原因之一,因此需要有效的饮食策略。发酵谷物传统上因对血糖调节、血脂状况和抗氧化活性有益而闻名,在管理2型糖尿病、高血压和肥胖等病症方面具有潜力。然而,它们对肝脏健康的具体影响需要进一步研究。发酵,特别是固态发酵(SSF),可提高包括酚类物质在内的有益化合物的生物利用度。本综述总结了近期关于发酵谷物酚类含量的研究,强调了基于微生物菌株和谷物类型的差异。它借鉴[具体文献1]和[具体文献2]的研究,探讨了这些酚类物质的肝脏保护作用。此外,本综述还探讨了近期关于发酵谷物对肝脏健康及相关疾病影响的研究结果。这项工作为未来探索将发酵谷物作为预防和管理肝脏疾病的饮食干预措施的研究奠定了基础。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5df1/11901820/9331023100bb/nutrients-17-00900-g001.jpg

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