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刚果民主共和国西部儿童和青少年的死亡率:对金佩塞卫生与人口监测系统的死因推断和人口数据的回顾性分析

Mortality in children and adolescents in Western Democratic Republic of Congo: retrospective analysis of verbal autopsy and demographic data from the Kimpese Health and Demographic Surveillance System.

作者信息

Fumwakwau Joël Kiniati, Schedwin Mattias, Ngale Mireille Amba, Hildenwall Helena, Alfven Tobias, Mapatano Mala Ali, King Carina, Phanzu Delphin Mavinga

机构信息

Kimpese Health Research Center, Kimpese, Congo (the Democratic Republic of the).

Institute for Economic and Social Research, University of Kinshasa, Kinshasa, Congo (the Democratic Republic of the).

出版信息

BMJ Paediatr Open. 2025 Mar 22;9(1):e003224. doi: 10.1136/bmjpo-2024-003224.

Abstract

BACKGROUND

There is a paucity of data on causes of death in children and adolescents that can be used for public health prioritisation in settings with the highest mortality burden. We aimed to estimate the causes and circumstances around deaths for the age group 1 month to 19 years in the Western Democratic Republic of Congo.

METHODS

Analysis of verbal autopsy and demographic data from the Kimpese Health and Demographic Surveillance System (rural setting 200 km west of Kinshasa) was collected between September 2018 and September 2021. About 66 000 individuals were surveyed yearly using structured questionnaires. Vital events were registered and identified deaths followed up with the World Health Organization 2012 or 2016 verbal autopsy questionnaire. Verbal autopsies were analysed using the InterVA-5 algorithm to generate cause of death and circumstances of mortality categories at the population level. Individual and household characteristics relevant to child survival were compared between deceased and surviving individuals using Fisher's exact test.

RESULTS

Overall, 166/273 (61%) of identified deaths had a complete verbal autopsy. 74% of deaths occurred in children 1-59 months of age, and 70% of all deaths were classified as due to infectious diseases. The top three causes were malaria (35%), lower respiratory infection (12%) and diarrhoeal disease (9%). 78% of deaths occurred at home, and <5% were considered inevitable. However, 70% of individuals sought healthcare in the days preceding death. Recognition (39%), emergencies (27%) and accessing care (20%) were the main contributing categories to fatal outcomes. Characteristics had low coverage (32-72% for the first dose of vaccinations and <10% for water, sanitation and hygiene).

CONCLUSIONS

Results suggest a need to sensitise caregivers about care-seeking, home treatment and danger signs and improve access to health facilities, combined with improving the quality of care in facilities. Improvements in access to safe water, sanitation and vaccination coverage are also needed.

摘要

背景

在死亡率负担最高的地区,可用于公共卫生优先事项安排的儿童和青少年死亡原因数据匮乏。我们旨在估计刚果民主共和国西部1个月至19岁年龄组的死亡原因及相关情况。

方法

对2018年9月至2021年9月期间从金沙萨以西200公里处的农村地区金佩塞卫生和人口监测系统收集的死因推断及人口统计数据进行分析。每年使用结构化问卷对约66000人进行调查。对生命事件进行登记,对于已确认的死亡,采用世界卫生组织2012年或2016年的死因推断问卷进行随访。使用InterVA - 5算法对死因推断进行分析,以在人群层面生成死亡原因及死亡情况类别。使用Fisher精确检验比较死亡个体和存活个体与儿童生存相关的个人及家庭特征。

结果

总体而言,166/273(61%)例已确认死亡病例有完整的死因推断。74%的死亡发生在1至59个月大的儿童中,所有死亡病例的70%被归类为传染病所致。前三大死因分别为疟疾(35%)、下呼吸道感染(12%)和腹泻病(9%)。78%的死亡发生在家中,且<5%被认为是不可避免的。然而,70%的个体在死亡前几天寻求过医疗护理。认知(39%)、紧急情况(27%)和获得护理(20%)是导致致命后果的主要因素。各项特征的覆盖率较低(首剂疫苗接种覆盖率为32 - 72%,水、环境卫生和个人卫生覆盖率<10%)。

结论

结果表明,有必要提高照料者对寻求医疗护理、家庭治疗和危险信号的认识,并改善获得卫生设施的机会,同时提高医疗机构的护理质量。还需要改善安全饮用水供应、环境卫生条件并提高疫苗接种覆盖率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf90/11931915/e659fdae4d75/bmjpo-9-1-g001.jpg

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