针灸和艾灸作为儿童单纯性肥胖的有效治疗方法：一项荟萃分析。
Acupuncture and moxibustion as effective treatments for simple obesity in children: a meta-analysis.
作者信息
Cui Fanghan
机构信息
School of Acupuncture and Tuina, Shandong University of Traditional Chinese Medicine Jinan 250300, Shandong, China.
出版信息
Am J Transl Res. 2025 Mar 15;17(3):1522-1537. doi: 10.62347/GWMP1676. eCollection 2025.
OBJECTIVE
To systematically review published studies on the application of acupuncture and moxibustion in the treatment of simple obesity in children and evaluate its effectiveness.
METHODS
A comprehensive search was conducted in the Wanfang, CNKI, Chinese Biomedical Literature, VIP, Embase, PubMed, Cochrane Library, and Web of Science for studies on the effects of acupuncture and moxibustion in treating simple obesity in children, published between December 2003 and October 2024. Primary clinical outcomes included blood lipids, fasting blood glucose, fasting insulin, weight-related indicators, clinical effects, leptin, body fat-related indicators, and traditional Chinese medicine (TCM) syndromes. Data were extracted and summarized, and a meta-analysis was performed using Revman 5.3 software and Stata 13.1.
RESULTS
A total of 20 studies met the inclusion criteria, all involving acupuncture and moxibustion therapy. Compared with the control group, acupuncture and moxibustion significantly reduced total cholesterol (TC) (SMD = -0.53; 95% CI: -0.95 to -0.12, P<0.0001, I = 87.3%), triglyceride (TG) (SMD = -0.27; 95% CI: -0.54 to -0.01, P = 0.002, I = 66.7%), and fasting blood glucose levels (SMD = -0.61; 95% CI: -1.08 to -0.13, I = 82.2%, P = 0.001). Compared to metformin group, semaglutide combined with metformin led to significant reductions in body mass indexes (BMI) (SMD = -0.49, 95% CI: -0.80 to -0.18, I = 81%). Additionally, acupuncture treatment resulted in a decrease in TCM syndrome scores compared to control therapy (SMD = -1.49; 95% CI = -2.73 to 0.25; I = 96.4%, P<0.0001).
CONCLUSION
Acupuncture and moxibustion treatment for simple obesity in children significantly reduced fasting blood glucose, waist circumference, TCM syndromes score, BMI and lipid levels.
目的
系统评价已发表的关于针灸治疗儿童单纯性肥胖症的研究，并评估其有效性。
方法
在万方、知网、中国生物医学文献数据库、维普、Embase、PubMed、Cochrane图书馆和Web of Science中全面检索2003年12月至2024年10月发表的关于针灸治疗儿童单纯性肥胖症疗效的研究。主要临床结局包括血脂、空腹血糖、空腹胰岛素、体重相关指标、临床疗效、瘦素、体脂相关指标和中医证候。提取并汇总数据，使用Revman 5.3软件和Stata 13.1进行荟萃分析。
结果
共有20项研究符合纳入标准，均涉及针灸疗法。与对照组相比，针灸显著降低了总胆固醇（TC）（标准化均数差[SMD]=-0.53；95%可信区间[CI]：-0.95至-0.12，P<0.0001，I²=87.3%）、甘油三酯（TG）（SMD=-0.27；95%CI：-0.54至-0.01，P=0.002，I²=66.7%）和空腹血糖水平（SMD=-0.61；95%CI：-1.08至-0.13，I²=82.2%，P=0.001）。与二甲双胍组相比，司美格鲁肽联合二甲双胍显著降低了体重指数（BMI）（SMD=-0.49，95%CI：-0.80至-0.18，I²=81%）。此外，与对照治疗相比，针灸治疗使中医证候评分降低（SMD=-1.49；95%CI=-2.73至0.25；I²=96.4%，P<0.0001）。
结论
针灸治疗儿童单纯性肥胖症可显著降低空腹血糖、腰围、中医证候评分、BMI和血脂水平。
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