Yanarueng Supachai, Prasit Nakarin, Phimha Surachai, Nonthamat Ampawan, Nilnate Nathakon, Nidthumsakul Nattaporn, Sresutham Puwanart
Sirindhorn College of Public Health Ubon Ratchathani, Ubon Ratchathani, Thailand.
Faculty of Public Health, Khon Kaen University, Khon Kaen, Thailand.
Sci Rep. 2025 Apr 16;15(1):13202. doi: 10.1038/s41598-025-97936-x.
The misuse of antibiotics has become a significant problem in Thailand and was particularly exacerbated after the COVID-19 pandemic. Increased access to antibiotics during the pandemic has led to a heightened risk of irrational antibiotic use. This study aimed to analyze the relationships and identify factors associated with antibiotic usage behavior among the Thai population. To examine the factors influencing antibiotic use behavior in Thailand post-COVID-19 and to provide recommendations for targeted interventions. This study utilized secondary data from the 2021 health and welfare survey conducted by the National Statistical Office of Thailand. A total sample of 25,833 individuals was analyzed using multiple logistic regression, adjusting for covariates including demographic factors, health status, and healthcare utilization patterns. The key factors influencing antibiotic use included experiencing illness (adjusted OR: 6.74, 95% CI: 6.11-7.44), sustaining injuries from accidents (adjusted OR: 2.84, 95% CI: 2.19-3.67), receiving dental care (adjusted OR: 1.44, 95% CI: 1.25-1.66), and illness without hospital admission (adjusted OR: 1.60, 95% CI: 1.23-2.10). Additionally, knowledge of antibiotic use was significantly associated with antibiotic use behavior, with those having low knowledge showing higher odds of antibiotic use compared to those with high knowledge (adjusted OR: 2.75, 95% CI: 2.32-3.27). The findings highlight the need for targeted interventions to address inappropriate antibiotic use. The government and relevant agencies should promote health awareness and literacy, develop effective medication, and implement stricter regulations to minimize the adverse effects of antibiotic misuse. Enhanced public education and ensuring access to accurate information from healthcare professionals are essential for mitigating the threat of antimicrobial resistance in Thailand.
抗生素的滥用已成为泰国的一个重大问题,在新冠疫情之后尤其加剧。疫情期间抗生素获取渠道增多,导致不合理使用抗生素的风险增加。本研究旨在分析泰国人群中抗生素使用行为之间的关系,并确定与之相关的因素。以研究新冠疫情后影响泰国抗生素使用行为的因素,并为有针对性的干预措施提供建议。本研究利用了泰国国家统计局2021年健康与福利调查的二手数据。使用多元逻辑回归分析了总共25833名个体的样本,并对包括人口因素、健康状况和医疗利用模式在内的协变量进行了调整。影响抗生素使用的关键因素包括患病(调整后的比值比:6.74,95%置信区间:6.11 - 7.44)、因事故受伤(调整后的比值比:2.84,95%置信区间:2.19 - 3.67)、接受牙科护理(调整后的比值比:1.44,95%置信区间:1.25 - 1.66)以及患病但未住院(调整后的比值比:1.60,95%置信区间:1.23 - 2.10)。此外,抗生素使用知识与抗生素使用行为显著相关,与知识水平高的人相比,知识水平低的人使用抗生素的几率更高(调整后的比值比:2.75,95%置信区间:2.32 - 3.27)。研究结果凸显了采取针对性干预措施以解决不适当抗生素使用问题的必要性。政府和相关机构应提高健康意识和素养,开发有效的药物,并实施更严格的法规,以尽量减少抗生素滥用的不良影响。加强公众教育并确保从医疗专业人员处获取准确信息对于减轻泰国抗菌药物耐药性的威胁至关重要。